ArticleJournal of virology1995
A subpopulation of normal B cells latently infected with Epstein-Barr virus resembles Burkitt lymphoma cells in expressing EBNA-1 but not EBNA-2 or LMP1.
Article in Journal of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 216 citations in OpenAlex.
- Exploring the nuclear proteins, viral capsid protein, and early antigen protein using immunoinformatic and molecular modeling approaches to design a vaccine candidate against Epstein Barr virus.Scientific reports · 2024Article
- Treatment Options for Epstein-Barr Virus-Related Disorders of the Central Nervous System.Infection and drug resistance · 2023Review
- Antibodies from Multiple Sclerosis Brain Identified Epstein-Barr Virus Nuclear Antigen 1 & 2 Epitopes which Are Recognized by Oligoclonal Bands.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021Article
- Review
- High Levels of IL-10 and CD4+CD25hi+ Treg Cells in Endemic Burkitt's Lymphoma Patients.Biomedicines · 2015Article
- Isotypes of Epstein-Barr virus antibodies in rheumatoid arthritis: association with rheumatoid factors and citrulline-dependent antibodies.BioMed research international · 2015Article
- EBV Persistence--Introducing the Virus.Current topics in microbiology and immunology · 2015Review
- Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection.PloS one · 2013Article
- Exploiting the interplay between innate and adaptive immunity to improve immunotherapeutic strategies for Epstein-Barr-virus-driven disorders.Clinical & developmental immunology · 2012Review
- Hematopoietic cells as sources for patient-specific iPSCs and disease modeling.Cell cycle (Georgetown, Tex.) · 2011Article
- Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells.Blood · 2011Article
- CTCF prevents the epigenetic drift of EBV latency promoter Qp.PLoS pathogens · 2010Article
- Burkitt's lymphoma: the Rosetta Stone deciphering Epstein-Barr virus biology.Seminars in cancer biology · 2009Review
- EBV in Hodgkin Lymphoma.Mediterranean journal of hematology and infectious diseases · 2009Article
- Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn.Journal of virology · 2008Article
- Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival.Blood · 2007Article
- Chronic herpesvirus reactivation occurs in aging.Experimental gerontology · 2007Article
- Epstein-Barr virus infection in humans: from harmless to life endangering virus-lymphocyte interactions.Oncogene · 2007Review
- Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity.Journal of virology · 2007Article
- Virus and cell RNAs expressed during Epstein-Barr virus replication.Journal of virology · 2006Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Using reverse transcription of whole cellular RNA and nested PCR, we have performed experiments mixing different proportions of Epstein-Barr virus (EBV)-carrying and EBV-negative cells. Based on the results, a method that detects viral transcripts for EBNA-1, EBNA-2, LMP1, and LMP2a from less than one positive cell among 10(5) negative cells was developed. With this method we have shown that the EBV DNA positive cells among small, high-density peripheral blood B-lymphocytes of normal healthy persons express EBNA-1-mRNA but not EBNA-2 or LMP1. A similar EBV expression pattern is found in type I Burkitt lymphoma cells. We suggest that the expression pattern in the lymphoma cells reflects the viral strategy in normal resting B cells and meets the requirements of latent persistence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.