ArticleVirus genes1995
Complete sequence of the RNA genome of human rhinovirus 16, a clinically useful common cold virus belonging to the ICAM-1 receptor group.
Article in Virus genes, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed, 65 citations in OpenAlex.
- Infection-specific long-chain fatty acid metabolism as a broad anti-enterovirus target.bioRxiv : the preprint server for biology · 2026Article
- Phytochemicals: Promising Inhibitors of Human Rhinovirus Type 14 3C Protease as a Strategy to Fight the Common Cold.Current topics in medicinal chemistry · 2024Article
- Anionic Pulmonary Surfactant Lipid Treatment Inhibits Rhinovirus A Infection of the Human Airway Epithelium.Viruses · 2023Article
- Development of a Rhinovirus Inoculum Using a Reverse Genetics Approach.The Journal of infectious diseases · 2019Article
- Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus.PLoS pathogens · 2018Article
- Human Rhinovirus Diversity and Evolution: How Strange the Change from Major to Minor.Journal of virology · 2017Article
- Neonatal immune response to rhinovirus A16 has diminished dendritic cell function and increased B cell activation.PloS one · 2017Article
- Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells.Virology · 2016Article
- Production, purification, and capsid stability of rhinovirus C types.Journal of virological methods · 2015Article
- Reverse genetics system for studying human rhinovirus infections.Methods in molecular biology (Clifton, N.J.) · 2015Article
- Human rhinovirus 16 causes Golgi apparatus fragmentation without blocking protein secretion.Journal of virology · 2014Article
- Capsid protein VP4 of human rhinovirus induces membrane permeability by the formation of a size-selective multimeric pore.PLoS pathogens · 2014Article
- Effects of rhinovirus species on viral replication and cytokine production.The Journal of allergy and clinical immunology · 2014Article
- Modeling of the human rhinovirus C capsid suggests possible causes for antiviral drug resistance.Virology · 2014Article
- PROPHYLACTIC ANTIBODY TREATMENT AND INTRAMUSCULAR IMMUNIZATION REDUCE INFECTIOUS HUMAN RHINOVIRUS 16 LOAD IN THE LOWER RESPIRATORY TRACT OF CHALLENGED COTTON RATS.Trials in vaccinology · 2014Article
- Budesonide and formoterol effects on rhinovirus replication and epithelial cell cytokine responses.Respiratory research · 2013Article
- Viral proteinase requirements for the nucleocytoplasmic relocalization of cellular splicing factor SRp20 during picornavirus infections.Journal of virology · 2013Article
- Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells.Virology · 2013Article
- Infection and propagation of human rhinovirus C in human airway epithelial cells.Journal of virology · 2012Article
- Comparison of rhinovirus A infection in human primary epithelial and HeLa cells.The Journal of general virology · 2011Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We report here the complete nucleotide sequence and predicted polyprotein sequence of HeLa cell-adapted human rhinovirus 16 (HRV16). This virus is more suitable than human rhinovirus 14 (HRV14) for clinical studies, and its growth and physical properties are favorable for biochemical and crystallographic analysis. The complete message-sense RNA genome of HRV16 is composed of 7124 bases, not including the poly(A) tail. An open reading frame, extending from base 626 to 7084 predicts a polyprotein containing 2152 amino acid residues. Comparison with other rhinovirus sequences shows HRV16 is much more representative of human rhinoviruses than HRV14. No apparent relationship was found between receptor group and amino acid sequence in VP1, the capsid protein bearing the binding site for the intercellular adhesion molecule-1 (ICAM-1) in both HRV14 and HRV16.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.