ArticleProceedings of the National Academy of Sciences of the United States of America1995
Oxygen as a key developmental regulator of Rhizobium meliloti N2-fixation gene expression within the alfalfa root nodule.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 151 citations in OpenAlex.
- Nutrient-dependent regulation of symbiotic nitrogen fixation in legumes.Horticulture research · 2025Article
- Symbiosis between Dendrobium catenatum protocorms and Serendipita indica involves the plant hypoxia response pathway.Plant physiology · 2023Article
- Control of the rhizobium-legume symbiosis by the plant nitrogen demand is tightly integrated at the whole plant level and requires inter-organ systemic signaling.Frontiers in plant science · 2023Review
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- The Oxidative Paradox in Low Oxygen Stress in Plants.Antioxidants (Basel, Switzerland) · 2021Review
- Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis.PLoS genetics · 2021Article
- Article
- Article
- Characterization of the Sinorhizobium meliloti HslUV and ClpXP Protease Systems in Free-Living and Symbiotic States.Journal of bacteriology · 2019Article
- Exploring Legume-Rhizobia Symbiotic Models for Waterlogging Tolerance.Frontiers in plant science · 2019Review
- A Novel Highly Efficient Device for Growing Micro-Aerophilic Microorganisms.Frontiers in microbiology · 2019Article
- Waterlogging tolerance, tissue nitrogen and oxygen transport in the forage legume Melilotus siculus: a comparison of nodulated and nitrate-fed plants.Annals of botany · 2018Article
- Characterization of Novel Plant Symbiosis Mutants Using a New Multiple Gene-Expression ReporterFrontiers in plant science · 2018Article
- Review
- Article
- Transcriptomic Insight in the Control of Legume Root Secondary Infection by theFrontiers in microbiology · 2017Article
- Transition Metal Transport in Plants and Associated Endosymbionts: Arbuscular Mycorrhizal Fungi and Rhizobia.Frontiers in plant science · 2016Review
- Short-Term Molecular Acclimation Processes of Legume Nodules to Increased External Oxygen Concentration.Frontiers in plant science · 2015Article
- The CCAAT box-binding transcription factor NF-YA1 controls rhizobial infection.Journal of experimental botany · 2014Article
- Shallow breathing: bacterial life at low O(2).Nature reviews. Microbiology · 2013Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The symbiotic pattern of expression of Rhizobium meliloti N2-fixation genes is tightly coupled with the histological organization of the alfalfa root nodule and thus is under developmental control. N2-fixation gene expression is induced very sharply at a particular zone of the nodule called interzone II-III that precedes the zone where N2 fixation takes place. We show here that this coupling can be disrupted, hereby resulting in ectopic expression of N2-fixation genes in the prefixing zone II of the nodule. Uncoupling was obtained either by using a R. meliloti strain in which a mutation rendered N2-fixation gene expression constitutive with respect to oxygen in free-living bacterial cultures or by placing nodules induced by a wild-type R. meliloti strain in a microoxic environment. These results implicate oxygen as a key determinant of the symbiotic pattern of N2-fixation gene expression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.