Evidence map›Paper›PMID 7724509›Full record

ArticleParasitology research1995

Effect of various doses of infective Toxocara canis and Toxocara cati eggs on the humoral response and distribution of larvae in mice.

K Havasiová-Reiterová, O Tomasovicová, P Dubinský

Abstract read
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In one paragraph

Article in Parasitology research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 80 citations in OpenAlex.

  1. Modelling the risk of food-borne transmission ofEpidemiology and infection · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Migratory pattern of zoonotic Toxocara cati and T. canis in experimentally infected pigs.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Larval distribution, migratory pattern and histological effects ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Prolactin as immune cell regulator inBioscience reports · 2018
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

K Havasiová-ReiterováParasitological Institute of the Slovak Academy of Sciences, Kosice.
O Tomasovicová
P Dubinský
Institute of Parasitology of the Slovak Academy of Sciences · SKSlovak Academy of Sciences · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of 5-2,500 infective Toxocara canis and 5-1,000 T. cati eggs on the humoral immune response and on the distribution of larvae in the organism was studied in paratenic hosts--inbred C57BL6/J mice. With each dose of T. canis eggs the maximal antibody level was recorded on day 56 post infection and was followed by a moderate decline that lasted until day 154 of the experiment. A correlation between the antibody level and the egg count was observed only with the infective dose of 5-50 eggs. A more rapid occurrence of antibodies was recorded in mice infected with a high dose of eggs. In those given 5 and 7 T. cati eggs the antibody level exceeded the extinction threshold value only from day 21 to day 84. Low doses of T. canis (n = 5) and T. cati (n = 7) eggs caused a comparable distribution of larvae in mice, and the larval recoveries on day 70 post infection ranged between 10.00% and 25.74%. Following a dose of 500 T. cati eggs, 22.28% of the larvae were recovered, although only 1.08% were localized in the brain. A dose of 1,000 T. canis eggs yielded 36.37% of the larvae, with as much as 28.13% being found in the brain.

Indexed as

AnimalsAntibodies, HelminthCatsDogsFemaleLarvaMaleMiceMice, Inbred C57BLOvumTissue DistributionToxocara canisToxocariasisAntibodies, Helminth

Identifiers

PMID7724509
OpenAlexW2017115792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.