ReviewEnvironmental health perspectives1994
Genetic and molecular ecotoxicology: a research framework.
Review in Environmental health perspectives, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Revisiting the genotoxic syndrome: Why are we overlooking the ecological impacts of genotoxins on animal populations?Genetics and molecular biology · 2025Article
- Molecular evidence for suppression of swimming behavior and reproduction in the estuarine rotifer Brachionus koreanus in response to COVID-19 disinfectants.Marine pollution bulletin · 2022Article
- Lee Raleigh Shugart.Ecotoxicology (London, England) · 2021Article
- The role of ascorbic acid combined exposure on Imidacloprid-induced oxidative stress and genotoxicity in Nile tilapia.Scientific reports · 2021Article
- Chronic radiation exposure at Chernobyl shows no effect on genetic diversity in the freshwater crustacean,Ecology and evolution · 2019Article
- Imidacloprid modifies the mitotic kinetics and causes both aneugenic and clastogenic effects in the macrophyteHeliyon · 2019Article
- Cytochrome P4501A mRNA and protein induction in striped bass (Morone saxatilis).Fish physiology and biochemistry · 2012Article
- QPCR: a tool for analysis of mitochondrial and nuclear DNA damage in ecotoxicology.Ecotoxicology (London, England) · 2010Review
- Comparative study of the sensitivity to cadmium of two populations of Gambusia affinis from two different sites.Environmental monitoring and assessment · 2009Article
- DNA strand length and EROD activity in relation to two screening measures of genotoxic exposure in Great Lakes herring gulls.Ecotoxicology (London, England) · 2005Article
- Rationale for a new generation of indicators for coastal waters.Environmental health perspectives · 2004Review
- Chemical contaminants and their effects in fish and wildlife from the industrial zone of Sumgayit, Republic of Azerbaijan.Ecotoxicology (London, England) · 2003Article
- The midgut epithelium of aquatic arthropods: a critical target organ in environmental toxicology.Environmental health perspectives · 2002Review
- Detection of cytogenetic alterations and blood cell changes in natural populations of carp.Ecotoxicology (London, England) · 2002Article
- Wildlife as sentinels of human health effects in the Great Lakes--St. Lawrence basin.Environmental health perspectives · 2001Article
- Cytochrome b sequences in black-crowned night-herons (Nycticorax nycticorax) from heronries exposed to genotoxic contaminants.Ecotoxicology (London, England) · 2001Article
- Marine swimming-related illness: implications for monitoring and environmental policy.Environmental health perspectives · 2001Review
- Responses of chub (Leuciscus cephalus) populations to chemical stress, assessed by genetic markers, DNA damage and cytochrome P4501A induction.Ecotoxicology (London, England) · 2001Article
- DNA fingerprint comparison of rainbow trout and RTG-2 cell line using random amplified polymorphic DNA.Ecotoxicology (London, England) · 2001Article
- Genetic susceptibility in ecosystems: the challenge for ecotoxicology.Environmental health perspectives · 1997Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Participants at the Napa Conference on Genetic and Molecular Ecotoxicology assessed the status of this field in light of heightened concerns about the genetic effects of exposure to hazardous substances and recent advancements in our capabilities to measure those effects. We present here a synthesis of the ideas discussed throughout the conference, including definitions of important concepts in the field and critical research needs and opportunities. While there were many opinions expressed on these topics, there was general agreement that there are substantive new opportunities to improve the impact of genetic and molecular ecotoxicology on prediction of sublethal effects of exposure to hazardous substances. Future studies should emphasize integration of genetic ecotoxicology, ecological genetics, and molecular biology and should be directed toward improving our understanding of the ecological implications of genotoxic responses. Ecological implications may be assessed at either the population or ecosystem level; however, a population-level focus may be most pragmatic. Recent technical advancements in measuring genetic and molecular responses to toxicant exposure will spur rapid progress. These new techniques have considerable promise for increasing our understanding of both mechanisms of toxicity on genes or gene products and the relevance of detrimental effects to individual fitness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.