Evidence map›Paper›PMID 7710945›Full record

ArticleBritish journal of cancer1995

Annexin VI has tumour-suppressor activity in human A431 squamous epithelial carcinoma cells.

J Theobald, A Hanby, K Patel, S E Moss

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in British journal of cancer, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Revisiting the role of Annexins in membrane trafficking.Cellular and molecular life sciences : CMLS · 2025
    Review
  3. Review
  4. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Review
  7. Role of annexin A6 in cancer.Oncology letters · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Annexin VII as a novel marker for invasive phenotype of malignant melanoma.Japanese journal of cancer research : Gann · 2000
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

J TheobaldDepartment of Physiology, University College London, UK.
A Hanby
K Patel
S E Moss
University College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study we show that heterologous expression of annexin VI in A431 squamous carcinoma cells caused a marked suppression of tumour cell growth when cells were cultured subcutaneously in nude mice. The tumours formed by the annexin VI+ A431 cells were morphologically and histologically similar to those formed by the wild-type cells.

Indexed as

AnimalsAnnexin A6Carcinoma, Squamous CellCell LineClone CellsHumansImmunohistochemistryMiceMice, NudeTransplantation, HeterologousTumor Cells, CulturedAnnexin A6

Identifiers

PMID7710945
PMCPMC2033739
OpenAlexW1972112307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.