ArticleProceedings of the National Academy of Sciences of the United States of America1995
Requirement for a phospholipase C in odor response: overlap between olfaction and vision in Drosophila.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 106 citations in OpenAlex.
- Heterologous investigation of metabotropic and ionotropic odorant receptors in ab3A neurons ofFrontiers in molecular biosciences · 2023Article
- Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors.Cell and tissue research · 2021Review
- Article
- Tuning Insect Odorant Receptors.Frontiers in cellular neuroscience · 2018Article
- Molecular basis of fatty acid taste ineLife · 2017Article
- Morphological and Transcriptomic Analysis of a Beetle Chemosensory System Reveals a Gnathal Olfactory Center.BMC biology · 2016Article
- Insect odorant response sensitivity is tuned by metabotropically autoregulated olfactory receptors.PloS one · 2013Article
- Loss of syd-1 from R7 neurons disrupts two distinct phases of presynaptic development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Rhodopsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster is independent of retinal phospholipase C-β signaling.Journal of biological rhythms · 2012Article
- High-resolution linkage analyses to identify genes that influence Varroa sensitive hygiene behavior in honey bees.PloS one · 2012Article
- Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism.Diabetes · 2011Article
- Towards plant-odor-related olfactory neuroethology in Drosophila.Chemoecology · 2010Article
- Controversy and consensus: noncanonical signaling mechanisms in the insect olfactory system.Current opinion in neurobiology · 2009Review
- Odorant and pheromone receptors in insects.Frontiers in cellular neuroscience · 2009Article
- Reduced odor responses from antennal neurons of G(q)alpha, phospholipase Cbeta, and rdgA mutants in Drosophila support a role for a phospholipid intermediate in insect olfactory transduction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction.Journal of insect physiology · 2008Article
- Taste and pheromone perception in the fruit fly Drosophila melanogaster.Pflugers Archiv : European journal of physiology · 2007Review
- Galpha encoding gene family of the malaria vector mosquito Anopheles gambiae: expression analysis and immunolocalization of AGalphaq and AGalphao in female antennae.The Journal of comparative neurology · 2006Article
- Control of daily transcript oscillations in Drosophila by light and the circadian clock.PLoS genetics · 2006Article
- Olfactory regulation of mosquito-host interactions.Insect biochemistry and molecular biology · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A central problem in sensory system biology is the identification of the signal transduction pathways used in different sensory modalities. Genetic analysis of transduction mutants provides a means of studying in vivo the contributions of different pathways. This report shows that odorant response in one olfactory organ of Drosophila melanogaster depends on the norpA phospholipase C (EC 3.1.4.3) gene, providing evidence for use of the inositol 1,4,5-trisphosphate (IP3) signal transduction pathway. Since the norpA gene is also essential to phototransduction, this work demonstrates overlap in the genetic and molecular underpinnings of vision and olfaction. Genetic and molecular data also indicate that some olfactory information flows through a pathway which does not depend on norpA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.