ArticleProceedings of the National Academy of Sciences of the United States of America1995
The rapid assembly of synaptic sites in photoreceptor terminals of the fly's optic lobe recovering from cold shock.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- The Architecture of the Presynaptic Release Site.Advances in neurobiology · 2023Article
- The Toll Route to Structural Brain Plasticity.Frontiers in physiology · 2021Review
- Effect of temperature change on synaptic transmission at crayfish neuromuscular junctions.Biology open · 2018Article
- The functional organisation of glia in the adult brain of Drosophila and other insects.Progress in neurobiology · 2010Review
- Brain plasticity in Diptera and Hymenoptera.Frontiers in bioscience (Scholar edition) · 2010Review
- Endophilin promotes a late step in endocytosis at glial invaginations in Drosophila photoreceptor terminals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Experience-dependent strengthening of Drosophila neuromuscular junctions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Persistent engrailed expression is required to determine sensory axon trajectory, branching, and target choice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
When a housefly, Musca domestica, is subject to cold exposure (0 degrees C for 24 hr), a number of obvious changes are seen in the first optic neuropil, or lamina, beneath the compound eye. In particular, the number of afferent photoreceptor synapses declines by about 30%. This loss is dramatically restored after warm recovery at 23 degrees C for 24 hr. Synapses disappear at an average rate of 2-3/hr during cold exposure and reappear at a maximal rate of more than 20/hr during the first 2 hr of warm recovery. Thereafter their number temporarily overshoots control values, to increase at 6 hr of warm recovery to 60% above their cold-exposed minimum. The number subsequently returns more or less to normal. These changes demonstrate the lability of synaptic sites under these conditions, with individual sites forming and disappearing rapidly. The changes also interrupt the close correlation between synaptic number and the surface area of the receptor terminal, a correlation that normally conserves synaptic spacing density. The density is preserved during cold exposure but increases during warm recovery at a time when the addition of newly formed synapses exceeds the slower increase in receptor terminal size.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.