ReviewMicrobiological reviews1995
Regulation of cellular differentiation in Caulobacter crescentus.
Review in Microbiological reviews, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 83 citations in OpenAlex.
- Distinct modes of cell division drivemBio · 2025Article
- The Periplasmic Tail-Specific Protease, Tsp, Is Essential for Secondary Differentiation inJournal of bacteriology · 2023Article
- Pleomorphic Variants ofInternational journal of molecular sciences · 2023Article
- Proteolysis dependent cell cycle regulation in Caulobacter crescentus.Cell division · 2022Review
- Dynamical modeling of the cell cycle and cell fate emergence in Caulobacter crescentus.PloS one · 2014Article
- Direct interaction of FliX and FlbD is required for their regulatory activity in Caulobacter crescentus.BMC microbiology · 2011Article
- A temperature-sensitive mutation in the dnaE gene of Caulobacter crescentus that prevents initiation of DNA replication but not ongoing elongation of DNA.Journal of bacteriology · 2004Article
- Temporal regulation of genes encoding the flagellar proximal rod in Caulobacter crescentus.Journal of bacteriology · 2001Article
- Cell cycle regulator phosphorylation stimulates two distinct modes of binding at a chromosome replication origin.The EMBO journal · 2000Article
- FlbT couples flagellum assembly to gene expression in Caulobacter crescentus.Journal of bacteriology · 1999Article
- Regulation of podJ expression during the Caulobacter crescentus cell cycle.Journal of bacteriology · 1999Article
- The CtrA response regulator mediates temporal control of gene expression during the Caulobacter cell cycle.Journal of bacteriology · 1999Article
- A new class of Caulobacter crescentus flagellar genes.Journal of bacteriology · 1998Article
- Cell cycle-dependent transcriptional and proteolytic regulation of FtsZ in Caulobacter.Genes & development · 1998Article
- An essential, multicomponent signal transduction pathway required for cell cycle regulation in Caulobacter.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Negative control of bacterial DNA replication by a cell cycle regulatory protein that binds at the chromosome origin.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Differential regulation of multiple flagellins in Vibrio cholerae.Journal of bacteriology · 1998Article
- Cloning of a Vibrio alginolyticus rpoN gene that is required for polar flagellar formation.Journal of bacteriology · 1997Article
- Identification of an essential Caulobacter crescentus gene encoding a member of the Obg family of GTP-binding proteins.Journal of bacteriology · 1997Article
- Identification of the fliI and fliJ components of the Caulobacter flagellar type III protein secretion system.Journal of bacteriology · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In Caulobacter crescentus, asymmetry is generated in the predivisional cell, resulting in the formation of two distinct cell types upon cell division: a motile swarmer cell and a sessile stalked cell. These progeny cell types differ in their relative programs of gene expression and DNA replication. In progeny swarmer cells, DNA replication is silenced for a defined period, but stalked cells reinitiate chromosomal DNA replication immediately following cell division. The establishment of these differential programs of DNA replication may be due to the polar localization of DNA replication proteins, differences in chromosome higher-order structure, or pole-specific transcription. The best-understood aspect of Caulobacter development is biogenesis of the polar flagellum. The genes encoding the flagellum are expressed under cell cycle control predominantly in the predivisional cell type. Transcription of flagellar genes is regulated by a trans-acting hierarchy that responds to both flagellar assembly and cell cycle cues. As the flagellar genes are expressed, their products are targeted to the swarmer pole of the predivisional cell, where assembly occurs. Specific protein targeting and compartmentalized transcription are two mechanisms that contribute to the positioning of flagellar gene products at the swarmer pole of the predivisional cell.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.