Evidence map›Paper›PMID 7693954›Full record

ArticleJournal of molecular evolution1993

Couplings of character and of chirality in the origin of the genetic system.

J C Lacey, N S Wickramasinghe, G W Cook, G Anderson, New Collective Author

Abstract read
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In one paragraph

Article in Journal of molecular evolution, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The beta-sheets of proteins, the biosynthetic relationships between amino acids, and the origin of the genetic code.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1996
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J C LaceyBiochemistry Department, University of Alabama at Birmingham 35294-2041.
N S Wickramasinghe
G W Cook
G Anderson
New Collective Author

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data from the literature and new data presented here suggest that the genetic system (coding and protein synthesis) is based on relationships of character and structure between amino acids and nucleic acids. Character relationships seem to be anticodonic and structurally the greatest preferences are seen between the heteropair, L-amino acids and D-ribose nucleic acids. However, living systems using the other heteropair must have been equally likely. Homopairing (L-L and D-D) in living systems seems unlikely. Awareness of the heterocoupling of steric forms narrows somewhat the problem of understanding the origin of chirality.

Indexed as

Genetic CodeMolecular ConformationAdenosineAmino AcidsAnticodonEsterificationNucleic Acid ConformationPhenylalanineRNAStereoisomerismAdenosineAmino AcidsAnticodonPhenylalanineRNANASA Discipline ExobiologyNon-NASA Center

Identifiers

PMID7693954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.