Evidence map›Paper›PMID 7692398›Full record

ArticleNucleic acids research1993

hnRNP G: sequence and characterization of a glycosylated RNA-binding protein.

M Soulard, V Della Valle, M C Siomi, S Piñol-Roma, P Codogno, C Bauvy, M Bellini, J C Lacroix, G Monod, G Dreyfuss

Open access · bronzeAbstract read
In one paragraph

Article in Nucleic acids research, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 142 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

M SoulardINSERM U-301, Institut de Génétique Moléculaire, Paris, France.
V Della Valle
M C Siomi
S Piñol-Roma
P Codogno
C Bauvy
M Bellini
J C Lacroix
G Monod
G Dreyfuss
Inserm · FRUniversity of Pennsylvania · USHoward Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The autoantigen p43 is a nuclear protein initially identified with autoantibodies from dogs with a lupus-like syndrome. Here we show that p43 is an RNA-binding protein, and identify it as hnRNP G, a previously described component of heterogeneous nuclear ribonucleoprotein complexes. We demonstrate that p43/hnRNP G is glycosylated, and identify the modification as O-linked N-acetylglucosamine. A full-length cDNA clone for hnRNP G has been isolated and sequenced, and the predicted amino acid sequence for hnRNP G shows that it contains one RNP-consensus RNA binding domain (RBD) at the amino terminus and a carboxyl domain rich in serines, arginines and glycines. The RBD of human hnRNP G shows striking similarities with the RBDs of several plant RNA-binding proteins.

Indexed as

AcetylglucosamineAmino Acid SequenceAnimalsChromosomesCloning, MolecularCulture Media, Serum-FreeDNA, ComplementaryGlycosylationHeLa CellsHeterogeneous-Nuclear RibonucleoproteinsHumansMolecular Sequence DataOocytesPleurodelesRibonucleoproteinsRNAAcetylglucosamineCulture Media, Serum-FreeDNA, ComplementaryHeterogeneous-Nuclear RibonucleoproteinsRibonucleoproteinsRNARNA-Binding Proteins

Identifiers

PMID7692398
PMCPMC310052
OpenAlexW1980168300

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.