Evidence map›Paper›PMID 7685079›Full record

ArticleNucleic acids research1993

A complex twintron is excised as four individual introns.

R G Drager, R B Hallick

Abstract read
In one paragraph

Article in Nucleic acids research, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Group II introns: mobile ribozymes that invade DNA.Cold Spring Harbor perspectives in biology · 2011
    Review
  8. Article
  9. Chloroplast ribosomes and protein synthesis.Microbiological reviews · 1994
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

R G DragerDepartment of Molecular and Cellular Biology, University of Arizona, Tucson 85721.
R B Hallick

Funding

SPLICING OF GROUP II AND GROUP III INTRONSR01GM035665 · NIGMS · UNIVERSITY OF ARIZONA · PI HALLICK, RICHARD B · 1985 to 2001
$583k
ORGANIZATION &EXPRESSION OF CHLOROPLAST TRNA GENESR01GM035625 · NIGMS · UNIVERSITY OF ARIZONA · PI HALLICK, RICHARD B · 1985 to 1993
–
NIGMS NIH HHS GM 35625NIGMS NIH HHS GM 35665
6 · The paper itself

Abstract

Twintrons are introns-within-introns excised by sequential splicing reactions. A new type of complex twintron comprised of four individual group III introns has been characterized. The external intron is interrupted by an internal intron containing two additional introns. This 434 nt complex twintron within a Euglena gracilis chloroplast ribosomal protein gene is excised by four sequential splicing reactions. Two of the splicing reactions utilize multiple 5'- and/or 3'-splice sites. These findings are evidence that introns with multiple active splice sites can be formed by the repeated insertion of introns into existing introns.

Indexed as

IntronsAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernChloroplastsCloning, MolecularDNAEuglena gracilisMolecular Sequence DataNucleic Acid ConformationPolymerase Chain ReactionRibosomal ProteinsRNARNA SplicingSequence Analysis, DNADNARibosomal ProteinsRNA

Identifiers

PMID7685079
PMCPMC309537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.