ArticleBiophysical journal1993
Measurement of rotational dynamics by the simultaneous nonlinear analysis of optical and EPR data.
Article in Biophysical journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Protein functional dynamics from the rigorous global analysis of DEER data: Conditions, components, and conformations.The Journal of general physiology · 2021Article
- A Straightforward Approach to the Analysis of Double Electron-Electron Resonance Data.Methods in enzymology · 2015Article
- CW dipolar broadening EPR spectroscopy and mechanically aligned bilayers used to measure distance and relative orientation between two TOAC spin labels on an antimicrobial peptide.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2014Article
- Distance measurements on a dual-labeled TOAC AChR M2δ peptide in mechanically aligned DMPC bilayers via dipolar broadening CW-EPR spectroscopy.The journal of physical chemistry. B · 2012Article
- Dipolar coupling between nitroxide spin labels: the development and application of a tether-in-a-cone model.Biophysical journal · 2006Article
- High field/high frequency saturation transfer electron paramagnetic resonance spectroscopy: increased sensitivity to very slow rotational motions.Biophysical journal · 2004Article
- The sensitivity of saturation transfer electron paramagnetic resonance spectra to restricted amplitude uniaxial rotational diffusion.Biophysical journal · 2001Article
- Flexibility of the cytoplasmic domain of the anion exchange protein, band 3, in human erythrocytes.Biophysical journal · 2001Article
- Comparison of electron paramagnetic resonance methods to determine distances between spin labels on human carbonic anhydrase II.Biophysical journal · 2001Article
- The conformation of serum albumin in solution: a combined phosphorescence depolarization-hydrodynamic modeling study.Biophysical journal · 2001Article
- Flexibility of duplex DNA on the submicrosecond timescale.Biophysical journal · 1999Article
- Molecular distances from dipolar coupled spin-labels: the global analysis of multifrequency continuous wave electron paramagnetic resonance data.Biophysical journal · 1997Article
- Overall and internal dynamics of DNA as monitored by five-atom-tethered spin labels.Biophysical journal · 1997Article
- Analysis of saturation transfer electron paramagnetic resonance spectra of a spin-labeled integral membrane protein, band 3, in terms of the uniaxial rotational diffusion model.Biophysical journal · 1995Article
- Resolution of multiphasic reactions by the combination of fluorescence total-intensity and anisotropy stopped-flow kinetic experiments.Biophysical journal · 1994Article
- Protein rotational dynamics investigated with a dual EPR/optical molecular probe. Spin-labeled eosin.Biophysical journal · 1993Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In the preceding companion article in this issue, an optical dye and a nitroxide radical were combined in a new dual function probe, 5-SLE. In this report, it is demonstrated that time-resolved optical anisotropy and electron paramagnetic resonance (EPR) data can be combined in a single analysis to measure rotational dynamics. Rigid-limit and rotational diffusion models for simulating nitroxide EPR data have been incorporated into a general non-linear least-squares procedure based on the Marquardt-Levenberg algorithm. Simultaneous fits to simulated time-resolved fluorescence anisotropy and linear EPR data, together with simultaneous fits to experimental time-resolved phosphorescence anisotropy decays and saturation transfer EPR (ST-EPR) spectra of 5-SLE noncovalently bound to bovine serum albumin (BSA) have been performed. These results demonstrate that data from optical and EPR experiments can be combined and globally fit to a single dynamic model.
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