ArticleProceedings of the National Academy of Sciences of the United States of America1993
Identification and preliminary characterization of a protein motif related to the zinc finger.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
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Who cites it
102 citing papers in PubMed.
- Smart responsive biomaterials for spatiotemporal modulation of functional tissue repair.Materials today. Bio · 2025Review
- Genome-Wide Identification of SRS Gene Family in Wheat and Expression Analysis Under Abiotic Stress.International journal of molecular sciences · 2025Article
- Study on molecular response of alfalfa to low temperature stress based on transcriptomic analysis.BMC plant biology · 2024Article
- Genome-wide identification of WRKY transcription factor family members in Miscanthus sinensis (Miscanthus sinensis Anderss).Scientific reports · 2024Article
- Evolutionary and Characteristic Analysis of RING-DUF1117 E3 Ubiquitin Ligase Genes inBiomolecules · 2021Article
- Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors.Cancers · 2021Review
- From 1957 to Nowadays: A Brief History of Epigenetics.International journal of molecular sciences · 2020Review
- The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunity.JCI insight · 2020Article
- Plant Cyclophilins: Multifaceted Proteins With Versatile Roles.Frontiers in plant science · 2020Review
- Association between single nucleotide polymorphisms within HLA region and disease relapse for patients with hematopoietic stem cell transplantation.Scientific reports · 2019Article
- RING-Domain E3 Ligase-Mediated Host-Virus Interactions: Orchestrating Immune Responses by the Host and Antagonizing Immune Defense by Viruses.Frontiers in immunology · 2018Review
- The Transcription Factor Function of Parkin: Breaking the Dogma.Frontiers in neuroscience · 2018Review
- Upregulation of the checkpoint protein CHFR is associated with tumor suppression in pancreatic cancers.Oncology letters · 2017Article
- Review
- Spatiotemporal Patterns of RING1 Expression after Rat Spinal Cord Injury.Neurochemical research · 2017Article
- Genome-wide characterisation and expression profile of the grapevine ATL ubiquitin ligase family reveal biotic and abiotic stress-responsive and development-related members.Scientific reports · 2016Article
- Article
- Article
- The RING Finger Ubiquitin E3 Ligase OsHTAS Enhances Heat Tolerance by Promoting H2O2-Induced Stomatal Closure in Rice.Plant physiology · 2016Article
- Wheat germ-based protein libraries for the functional characterisation of the Arabidopsis E2 ubiquitin conjugating enzymes and the RING-type E3 ubiquitin ligase enzymes.BMC plant biology · 2015Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have identified a protein motif, related to the zinc finger, which defines a newly discovered family of proteins. The motif was found in the sequence of the human RING1 gene, which is proximal to the major histocompatibility complex region on chromosome six. We propose naming this motif the "RING finger" and it is found in 27 proteins, all of which have putative DNA binding functions. We have synthesized a peptide corresponding to the RING1 motif and examined a number of properties, including metal and DNA binding. We provide evidence to support the suggestion that the RING finger motif is the DNA binding domain of this newly defined family of proteins.
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