ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery1993
Cochlear-motor, transduction and signal-transfer tinnitus: models for three types of cochlear tinnitus.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Sound therapy (masking) in the management of tinnitus in adults.The Cochrane database of systematic reviews · 2012Pooled it
- Treatment of central and sensorineural tinnitus with orally administered Melatonin and Sulodexide: personal experience from a randomized controlled study.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2009Trial
- An evaluation of magnetic resonance imaging with histogram analysis in patients with idiopathic subjective tinnitus.Northern clinics of Istanbul · 2019Article
- Medium-level laser in chronic tinnitus treatment.BioMed research international · 2013Article
- The role of plasma melatonin and vitamins C and B12 in the development of idiopathic tinnitus in the elderly.Ghana medical journal · 2012Article
- Pattern of brain blood perfusion in tinnitus patients using technetium-99m SPECT imaging.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012Article
- Functional brain abnormalities localized in 55 chronic tinnitus patients: fusion of SPECT coincidence imaging and MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2010Article
- Acute hyperpolarization and elongation of cochlear outer hair cells on superfusion with cis-platinum.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 1995Article
- Neural mechanisms of tinnitus.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 1993Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present paper reviews possible molecular and cellular mechanisms in the cochlea that might contribute to tinnitus. They constitute a part of a highly integrated network in cochlear sound processing and are divided for easier understanding into three different models, i.e. active motor tinnitus, transduction tinnitus and signal-transfer tinnitus. Some of the steps of the pathophysiological models can even be pharmacologically influenced (as exemplified by experimental applications of lidocaine, calcium channel blocker, benzodiazepine, glutamate and atropine). This provides a rationale for the efficient suppression of tinnitus in some patients by these drugs. The most evident problem of all models in tinnitus, including the ones proposed in this paper, is the lack of objective verification by measurement. Thus, the well-defined clinical situation of each patient is hardly attributable to one of the models suggested. In addition, adequate therapy--perhaps one of the drugs considered--still cannot be based upon a reliable clinical finding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.