Evidence map›Paper›PMID 7677729›Full record

ArticleBiochemical genetics1995

Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations.

O Koiwai, K Hasada, Y Yasui, Y Sakai, H Sato, T Watanabe

Abstract read
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Article in Biochemical genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

O KoiwaiDepartment of Biochemistry, Aichi Cancer Center Institute, Nagoya, Japan.
K Hasada
Y Yasui
Y Sakai
H Sato
T Watanabe
Aichi Developmental Disability Center · JPAichi Cancer Center · JPShiga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mouse gene for phenol UDP-glucuronosyltransferase (UDPGT; Ugtla1) was mapped at 42 cM on chromosome 1, a position identical to that of the gene for bilirubin UDPGT (Ugtla1), from linkage analysis of a three-point cross test with Idh-1, En-1, and Ugtla1 as marker genes. The cDNAs for mouse phenol and bilirubin UDPGTs, isolated after amplification by PCR, shared an identical 3'-half region. Our results strongly suggest that mouse bilirubin and phenol UDPGTs are expressed from a single gene and involve alternative splicing events. We also detected duplication of the gene for phenol UDPGT in all mouse strains examined with the exception of MOL-MIT and SUB-SHH.

Indexed as

Chromosome MappingAnimalsBase SequenceBlotting, SouthernChromosomes, Human, Pair 1Cloning, MolecularDNA, ComplementaryGene ExpressionGenetic LinkageGlucuronosyltransferaseHumansIn Situ HybridizationMiceMice, Inbred BALB CMice, Inbred C3HMice, Inbred C57BLbilirubin glucuronoside glucuronosyltransferaseDNA, ComplementaryGlucuronosyltransferaseRNA, Messenger

Identifiers

PMID7677729
OpenAlexW1968090001

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.