Evidence map›Paper›PMID 7672663›Full record

ArticleGut1995

Parallel interleukin 5 synthesis by eosinophils in duodenal and skin lesions of a patient with dermatitis herpetiformis.

P Desreumaux, A Janin, E Delaporte, S Dubucquoi, F Piette, A Cortot, M Capron, J F Colombel

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Gut, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

P DesreumauxClinique des Maladies de l'Appareil Digestif, Hôpital Claude Huriez, Centre Hospitalier Régional Universitaire (CHRU), Lille, France.
A Janin
E Delaporte
S Dubucquoi
F Piette
A Cortot
M Capron
J F Colombel
Hôpital Claude Huriez · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 59 year old man is presented with a diagnosis of dermatitis herpetiformis. Duodenal and skin biopsy specimens from blisters of both recent and late onset were collected before treatment. Electron microscopy, immunohistochemistry, and in situ hybridisation were performed to analyse the presence of activated eosinophils and the local synthesis of interleukin 5 (IL5). Parallel state of eosinophil activation and IL5 synthesis was found in the duodenal mucosa with total flat mucosa and in skin vesicles of recent onset. It is suggested that duodenal and cutaneous eosinophils can synthesise IL5 and then participate in small bowel and skin lesions.

Indexed as

Dermatitis HerpetiformisDuodenumEosinophilsHumansImmunohistochemistryIn Situ HybridizationInterleukin-5Intestinal MucosaMaleMicroscopy, ElectronMiddle AgedSkinInterleukin-5

Identifiers

PMID7672663
PMCPMC1382784
OpenAlexW2065212876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.