ArticleActa neurochirurgica1995
Use of positron emission tomography (PET) in stereotactic conditions for brain biopsy.
Article in Acta neurochirurgica, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review evaluating the effectiveness of nuclear medicine techniques in enhancing the diagnostic accuracy of stereotactic brain biopsies.Neurosurgical review · 2025Pooled it
- The role of biopsy in the management of patients with presumed diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.Journal of neuro-oncology · 2015Guideline
- PET Molecular Imaging-Directed Biopsy: A Review.AJR. American journal of roentgenology · 2017Review
- Diagnostic and Prognostic Value of 11C-Methionine PET for Nonenhancing Gliomas.AJNR. American journal of neuroradiology · 2016Article
- Usefulness of PET Imaging to Guide Treatment Options in Gliomas.Current treatment options in neurology · 2016Article
- Cost-effectiveness analysis of FET PET-guided target selection for the diagnosis of gliomas.European journal of nuclear medicine and molecular imaging · 2012Article
- PET imaging in the surgical management of pediatric brain tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2007Article
- Use of a disposable real-time CT stereotactic navigator device for minimally invasive dog brain biopsy through a mini-burr hole.AJNR. American journal of neuroradiology · 2002Article
- Positron emission tomography in patients with primary CNS lymphomas.Journal of neuro-oncology · 1999Review
- Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose.European journal of nuclear medicine · 1996Review
- Three- to five-dimensional biomedical multisensor imaging for the assessment of neurological (dys) function.Journal of digital imaging · 1996Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to take advantage of the metabolic information provided by positron emission tomography (PET) in cases of brain tumour, we have developed a technique to integrate PET images routinely in the planning of stereotactic brain biopsy. We used stereotactic PET with [18F]-labelled fluorodeoxyglucose (PET-FDG) in 38 patients undergoing brain biopsy. To evaluate the contribution of PET-FDG in guiding brain biopsy, we analyzed the diagnosis provided by the 78 stereotactic trajectories obtained in these patients. We found that stereotactic PET-FDG seemed to provide more information in cases of anaplastic astrocytomas and glioblastomas than in low-grade gliomas. Our results also show that biopsy trajectories performed in areas where increased FDG uptake is found within the lesion boundaries always provide interpretable specimens; this was not the case for trajectories guided by CT only. Therefore, the routine integration PET-FDG in the planning of stereotactic brain biopsy may lead to a reduction in sampling. Recently, we also tested consecutive stereotactic PET with [11C]-labelled methionine (PET-Met) and PET-FDG. This technique allowed us to compare accurately the tumoural glucose metabolism and protein synthesis. Our results suggest that stereotactic PET may increase the diagnostic yield of brain biopsy and may improve the understanding of PET in neuro-oncology.
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Registered trials
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