Evidence map›Paper›PMID 7665670›Full record

ArticleJournal of clinical microbiology1995

Sandwich enzyme-linked immunosorbent assay compared with Pastorex latex agglutination test for diagnosing invasive aspergillosis in immunocompromised patients.

P E Verweij, D Stynen, A J Rijs, B E de Pauw, J A Hoogkamp-Korstanje, J F Meis

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.

  1. Aspergillus Polymerase Chain Reaction: Systematic Review of Evidence for Clinical Use in Comparison With Antigen Testing.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Serum galactomannan levels in the diagnosis of invasive aspergillosis.The Korean journal of internal medicine · 2015
    Article
  7. Article
  8. Development of monoclonal antibody-based galactomannoprotein antigen-capture ELISAs to detect Aspergillus fumigatus infection in the invasive aspergillosis rabbit models.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012
    Article
  9. Article
  10. Article
  11. Current status of fungal cell wall components in the immunodiagnostics of invasive fungal infections in humans: galactomannan, mannan and (1-->3)-beta-D-glucan antigens.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2007
    Review
  12. A comparison of galactomannan-ELISA and a newly developed galactomannan-LATEX test in the serologic diagnosis of invasive aspergillosis in patients with hematologic malignancies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2007
    Article
  13. [Serological tests for diagnosing fungal infections].Wiener medizinische Wochenschrift (1946) · 2007
    Article
  14. Article
  15. Article
  16. Aspergillus infections in transplant recipients.Clinical microbiology reviews · 2005
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

P E VerweijDepartment of Medical Microbiology, University Hospital Nijmegen, The Netherlands.
D Stynen
A J Rijs
B E de Pauw
J A Hoogkamp-Korstanje
J F Meis
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance of a direct sandwich enzyme-linked immunosorbent assay (ELISA) for detecting Aspergillus galactomannan was compared with that of the Pastorex Aspergillus antigen latex agglutination (LA) test by using 532 serum samples from 61 patients at risk for invasive aspergillosis. The ELISA gave positive results earlier in the course of infection than did the LA test. A sensitivity of 70% and a specificity of 86% were obtained for the LA test and corresponding values of 90 and 84% were obtained for the ELISA when a series of serum samples was employed.

Indexed as

AdultAntigens, FungalAspergillosisAspergillus fumigatusEnzyme-Linked Immunosorbent AssayEvaluation Studies as TopicFemaleHumansImmunocompromised HostLatex Fixation TestsLung Diseases, FungalMaleMiddle AgedSensitivity and SpecificityAntigens, Fungal

Identifiers

PMID7665670
PMCPMC228297
OpenAlexW2158672061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.