Evidence map›Paper›PMID 7658464›Full record

ArticleThe Journal of membrane biology1995

Expression of a novel sodium-hydrogen exchanger in the gastrointestinal tract and kidney.

F K Ghishan, S Knobel, J A Barnard, M Breyer

Abstract read
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In one paragraph

Article in The Journal of membrane biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 22 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

F K GhishanDepartment of Pediatrics, Vanderbilt Medical School, Nashville, Tennessee 37232, USA.
S Knobel
J A Barnard
M Breyer
Vanderbilt University · US

Funding

DEVELOPMENT OF INTESTINAL ION TRANSPORTR01DK041274 · NIDDK · VANDERBILT UNIVERSITY · PI GHISHAN, FAYEZ KHALAF, KIELA, PAWEL R · 1988 to 2016
$5.5M
NCPDCID CDC HHS CIA K08 08193NIDDK NIH HHS DK RO1 41274
6 · The paper itself

Abstract

We have recently cloned a novel Na+/H+ exchanger (NHE-2) from rat small intestinal cDNA library. The present report characterizes the expression of (NHE-2) mRNA in the rat small intestine, stomach, and kidney using Northern blot analysis and in situ hybridization techniques. NHE-2 mRNA was detected in the surface epithelium of the stomach, villus but not crypt epithelial cells of the small intestine and in the distal convoluted, but not in the proximal tubules of the kidney. This distribution suggests a functional role in the transport of sodium across the apical membrane of the gastrointestinal tract and the kidney.

Indexed as

Alternative SplicingAnimalsAntisense Elements (Genetics)Blotting, NorthernDigestive SystemDNA, ComplementaryEpitheliumGastric MucosaGene ExpressionIn Situ HybridizationJejunumKidneyMaleRatsSodium-Hydrogen ExchangersAntisense Elements (Genetics)DNA, ComplementarySlc9a2 protein, ratSodium-Hydrogen Exchangers

Identifiers

PMID7658464
OpenAlexW2009847006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.