The unfolding story of megalin (gp330): now recognized as a drug receptor.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

5 citing papers in PubMed.

1. Association between low density lipoprotein receptor-related protein 2 gene polymorphisms and bone mineral density variation in Chinese population.PloS one · 2011
   Article
2. Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2006
   Article
3. Megalin binds and internalizes angiotensin-(1-7).American journal of physiology. Renal physiology · 2006
   Article
4. Molecular analysis of the pathological autoimmune antigens of Heymann nephritis.The American journal of pathology · 1996
   Review
5. Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.Proceedings of the National Academy of Sciences of the United States of America · 1996
   Article

Corrections and comments

• Comment on
  Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.1995

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as