Evidence map›Paper›PMID 7649782›Full record

ArticleJournal of anatomy1994

Pancreatic duct inflammatory infiltration in the nonobese diabetic (NOD) mouse.

G Papaccio, G C Baccari, C Strate, T Linn

Abstract read
In one paragraph

Article in Journal of anatomy, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Non-obese diabetic (NOD) mouse.The American journal of pathology · 1996
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G PapaccioInstitute of Anatomy, School of Medicine, 2nd University of Naples, Italy.
G C Baccari
C Strate
T Linn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pancreatic duct system during the early stages of type 1 diabetes was examined in 8-wk-old female nonobese diabetic (NOD) mice. Infiltration was seen to involve the smaller ducts while the larger ducts were usually free from ductulitis. The infiltration affected ducts both close to and remote from the islets of Langerhans. In the former situation, infiltration of the islet and that of the duct were not separable. A strong positivity for both Ia and ICAM-1 molecules was observed in all infiltrated ducts, indicating that this infiltrating process is due to the same elements as are involved in the islet inflammation and that also mononuclear cells infiltrating the nonislet ducts express adhesive mechanisms. At the ultrastructural level, endocrine cells that were mainly of the 'closed' type were observed intermingled with the ductular epithelial cells and infiltrating mononuclear cells were detected either in the connective layer or among the epithelial cells of the affected ducts.

Indexed as

AnimalsDiabetes Mellitus, Type 1FemaleHLA-D AntigensImmunohistochemistryIntercellular Adhesion Molecule-1LymphocytesMiceMice, Inbred NODMonocytesPancreatic DuctsPancreatitisHLA-D AntigensIntercellular Adhesion Molecule-1

Identifiers

PMID7649782
PMCPMC1166651
OpenAlexW1870571008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.