ArticleHistochemistry and cell biology1995
Distribution of E-cadherin and Ep-CAM in the human lung during development and after injury.
Article in Histochemistry and cell biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 54 citations in OpenAlex.
- Cell Adhesion Molecules in Fibrotic Diseases.Biomedicines · 2023Review
- Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract.Developmental cell · 2020Article
- Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology.Scientific reports · 2018Article
- Alveolar epithelial disintegrity in pulmonary fibrosis.American journal of physiology. Lung cellular and molecular physiology · 2016Review
- Infection of mice with influenza A/WSN/33 (H1N1) virus alters alveolar type II cell phenotype.American journal of physiology. Lung cellular and molecular physiology · 2015Article
- EpCAM and the biology of hepatic stem/progenitor cells.American journal of physiology. Gastrointestinal and liver physiology · 2015Review
- Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.Respiratory research · 2014Article
- Visualizing the beta interferon response in mice during infection with influenza A viruses expressing or lacking nonstructural protein 1.Journal of virology · 2013Article
- Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.American journal of respiratory cell and molecular biology · 2011Article
- Antiviral CD8+ T cell effector activities in situ are regulated by target cell type.The Journal of experimental medicine · 2011Article
- Epithelial N-cadherin and nuclear β-catenin are up-regulated during early development of human lung.BMC developmental biology · 2010Article
- HTII-280, a biomarker specific to the apical plasma membrane of human lung alveolar type II cells.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2010Article
- Dual-immunohistochemistry provides little evidence for epithelial-mesenchymal transition in pulmonary fibrosis.Histochemistry and cell biology · 2008Article
- Role of the mucosal integrin alpha(E)(CD103)beta(7) in tissue-restricted cytotoxicity.Clinical and experimental immunology · 2007Article
- Epithelial vs myofibroblast differentiation in immortal rat lung cell lines--modulating effects of bleomycin.Histochemistry and cell biology · 2005Article
- The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology.The American journal of pathology · 2003Review
- Primary human alveolar epithelial cells can elicit the transendothelial migration of CD14+ monocytes and CD3+ lymphocytes.Immunology · 2001Article
- Alveolar epithelial type II cell: defender of the alveolus revisited.Respiratory research · 2001Review
- Expression of CD44 isoforms during bleomycin-or radiation-induced pulmonary fibrosis in rats and mini-pigs.Histochemistry and cell biology · 1996Article
- Immunohistochemical evidence for loss of ICAM-1 by alveolar epithelial cells in pulmonary fibrosis.Histochemistry and cell biology · 1995Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paraffin sections were obtained of human fetal, adult, and pathological lung (pulmonary fibrosis after radiotherapy or chemotherapy). The localization of epithelial adhesion molecules E-cadherin and Ep-CAM (former epithelial surface 40 kDa glycoprotein) was investigated by immunoperoxidase and/or immunofluorescence techniques with monoclonal antibodies. During development, the epithelia of the primary pulmonary primordium, the secondary bronchi and the adult bronchial epithelium retained immunoreactivity for E-cadherin and Ep-CAM with lateral immunostaining of cell membranes. In normal adult lungs, Ep-CAM was detected in type I and II alveolar epithelial cells, whereas E-cadherin was confined to the basolateral domain of type II cells. In pulmonary fibrosis, Ep-CAM could be further detected on the cell surface of epithelial remnants. In contrast, E-cadherin expression was characterized by a change of the membrane localization to a spotty, cytoplasmic pattern in the alveolar epithelium, possibly indicating functional inactivation of the protein during fibrogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.