Evidence map›Paper›PMID 7646358›Full record

ArticleArchives of virology1995

Comparative nucleotide and deduced amino acid sequence analysis of VP7 gene of the NCDV Cody (I-801) strain of group A bovine rotavirus.

K O Chang, A V Parwani, L J Saif

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Article in Archives of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

K O ChangDepartment of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, Ohio State University, Wooster, USA.
A V Parwani
L J Saif

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalent G serotypes of group A bovine rotavirus (BRV) reported are G6, G10, and less commonly, G8. Neonatal Calf Diarrhea Virus (NCDV), Lincoln and Cody strains were first isolated from diarrheic calves in Nebraska. The NCDV Lincoln strain is the currently used U.S. vaccine strain and has a G6 serotype. In this study, the complete nucleotide sequence of the VP7 gene of NCDV Cody (I-801 strain) was determined using the primer extension method. The VP7 gene nucleotide sequence homologies between Cody I-801 and established G8 rotaviruses, A5 (Thailand BRV), 678 (UK BRV), B37 (human RV) and 69M (human RV) were 84.7%, 86.4%, 84.7% and 85.9%, respectively. The deduced VP7 amino acid sequence of Cody I-801 was similar to that of A5, 678, B37 and 69M (93.6%, 95.7%, 92.6% and 95.1%, respectively). The VP7 gene nucleic acid sequence homologies between NCDV Cody (I-801) and NCDV Lincoln or B223 (G10) was 76.2% and the deduced VP7 amino acid sequence homologies between Cody I-801 and NCDV Lincoln or B223 were 82.5% and 81.3%, respectively. Thus, our sequence data suggests that the VP7 gene of Cody I-801 strain of BRV is genetically most similar to G8 rotaviruses and unrelated to the NCDV Lincoln G6 rotavirus strain.

Indexed as

Antigens, ViralCapsid ProteinsAmino Acid SequenceAnimalsBase SequenceCapsidCattleCell LineDNA, ViralHaplorhiniHumansMolecular Sequence DataRotavirusSequence Homology, Amino AcidAntigens, ViralCapsid ProteinsDNA, ViralVP7 protein, Rotavirus

Identifiers

PMID7646358

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