Evidence map›Paper›PMID 7643960›Full record

ReviewNeurochemical research1995

Expression and regulation of kainate and AMPA receptors in uncommitted and committed neural progenitors.

V Gallo, M Pende, S Scherer, M Molné, P Wright

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Glutamate antagonists limit tumor growth.Proceedings of the National Academy of Sciences of the United States of America · 2001
    Article
  5. Glutamate antagonists: deadly liaisons with cancer.Proceedings of the National Academy of Sciences of the United States of America · 2001
    Article
  6. Growth factor-induced transcription of GluR1 increases functional AMPA receptor density in glial progenitor cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

V GalloUnit on Neurobiology, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland 20892, USA.
M Pende
S Scherer
M Molné
P Wright
National Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we review experimental evidence of non-NMDA glutamate receptor expression in the embryonic central nervous system. AMPA- and kainate-preferring glutamate receptor subunit mRNA transcripts are detected in embryonic neurons, glia and neural progenitors. Functional assays demonstrate that in some cell subpopulations ionotropic glutamate receptors are expressed by progenitors before synapse formation and terminal differentiation, and may be present before lineage determination is specified. The activation of these receptors triggers induction of immediate early gene transcription in progenitor cells. The cloning and transcriptional analysis of upstream regulatory regions of glutamate receptor genes governing their temporal and tissue-specific expression are also discussed.

Indexed as

AnimalsCells, CulturedHumansKainic Acid ReceptorsNeurogliaNeuronsReceptors, AMPAReceptors, GlutamateStem CellsTumor Cells, CulturedKainic Acid ReceptorsReceptors, AMPAReceptors, Glutamate

Identifiers

PMID7643960
OpenAlexW2089098396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.