Evidence map›Paper›PMID 7642274›Full record

ArticleInfection and immunity1995

Adhesion of Candida albicans to brain tissue of Macaca mulata in an ex vivo assay.

F J Denaro, J L López-Ribot, W L Chaffin

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. CouldJournal of clinical medicine · 2022
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

F J DenaroDepartment of Neurology, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
J L López-Ribot
W L Chaffin
Texas Tech University · US

Funding

ENTACTIN BINDING PROTEINS OF CANDIDA ALBICANSR01AI023416 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI CHAFFIN, WELDA LAJEAN · 1986 to 1999
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HISTOCHEMICAL CORRELATES OF AIDS DEMENTIA COMPLEXR29NS031857 · NINDS · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI DENARO, FRANK J · 1993 to 1997
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NIAID NIH HHS AI 23416NINDS NIH HHS NS 31857
6 · The paper itself

Abstract

An ex vivo adhesion assay was used to examine adhesion of Candida albicans yeast cells to brain tissue of the primate Macaca mulata. Tissues from frontal lobes and striatum (caudate, putamen, and portions of the globus pallidus) were used in the assay. Yeast cells adhered to gray matter at about six times the level of adhesion to white matter. The fungus was able to bind to different cell types within the cortex, basal ganglia, and white matter. Binding to neurons, small neurons or glia, endothelial cells, and neuropil was observed.

Indexed as

AdhesivenessAnimalsBrainCandida albicansMacaca mulatta

Identifiers

PMID7642274
PMCPMC173473
OpenAlexW2171440467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.