ArticleGenetics1995
Inversions with deletions and duplications.
Article in Genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Genotype-phenotype correlation of deletions and duplications of 4p: case reports and literature review.Frontiers in genetics · 2023Article
- The roles of replication-transcription conflict in mutagenesis and evolution of genome organization.PLoS genetics · 2020Review
- Transcription infidelity and genome integrity: the parallax view.Transcription · 2018Article
- The extreme dwarf phenotype of the GA-sensitive mutant of sunflower, dwarf2, is generated by a deletion in the ent-kaurenoic acid oxidase1 (HaKAO1) gene sequence.Plant molecular biology · 2011Article
- Complex human chromosomal and genomic rearrangements.Trends in genetics : TIG · 2009Review
- On the paucity of duplicated genes in Caenorhabditis elegans operons.Journal of molecular evolution · 2006Article
- The structure and early evolution of recently arisen gene duplicates in the Caenorhabditis elegans genome.Genetics · 2003Article
- Evidence for symmetric chromosomal inversions around the replication origin in bacteria.Genome biology · 2000Article
- Escape from het-6 incompatibility in Neurospora crassa partial diploids involves preferential deletion within the ectopic segment.Genetics · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complex mutational events, including de novo inversion with deletion and duplication of sequence, have been observed but are difficult to model. We propose that nascent leading-strand misalignment upon the lagging-strand template during DNA replication can result in the inversion of sequence. The positioning of this misalignment and of the realignment of the leading strand back into the leading-strand template will determine if the inversion is accompanied by deletion and duplication of sequence. We suggest that such strand misalignment-realignment events may occur at the replication fork during concurrent DNA replication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.