ArticleGenetics1995
Molecular evolution of flower development: diversification of the plant MADS-box regulatory gene family.
Article in Genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
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Who cites it
118 citing papers in PubMed, 403 citations in OpenAlex.
- Functional divergence of MADS-box genes and the dual regulatory role of a long noncoding RNA underlie sex determination in Ginkgo biloba.BMC plant biology · 2026Article
- Whole-genome resequencing of 495Horticulture research · 2026Article
- Article
- Dehiscent fruits in Brassicaceae and Papaveraceae: convergent morpho-anatomical features with divergent underlying genetic mechanisms.Annals of botany · 2025Article
- The homeotic gene PhDEF regulates production of volatiles in petunia flowers by activating EOBI and EOBII.The Plant cell · 2025Article
- Evolutionary Dynamics and Expression Divergence of thePlants (Basel, Switzerland) · 2025Article
- Defining petal cell identity layer-by-layer.The Plant cell · 2024Article
- Cell layer-specific expression of the homeotic MADS-box transcription factor PhDEF contributes to modular petal morphogenesis in petunia.The Plant cell · 2024Article
- Comparative transcriptomic analysis reveals differences inEcology and evolution · 2023Article
- Genomic insights into genetic diploidization in the homosporous fern Adiantum nelumboides.Genome biology and evolution · 2022Article
- Genome‑wide identification, phylogenetic and expression pattern analysis of GATA family genes in foxtail millet (Setaria italica).BMC genomics · 2022Article
- The slow-evolving Acorus tatarinowii genome sheds light on ancestral monocot evolution.Nature plants · 2022Article
- The MADS-box gene FveSEP3 plays essential roles in flower organogenesis and fruit development in woodland strawberry.Horticulture research · 2021Article
- Genome-wide comparative analyses of GATA transcription factors among seven Populus genomes.Scientific reports · 2021Article
- Hypothesis-based food, feed, and environmental safety assessment of GM crops: A case study using maize event DP-202216-6.GM crops & food · 2021Review
- The Transcriptome of Cunninghamia lanceolata male/female cone reveal the association between MIKC MADS-box genes and reproductive organs development.BMC plant biology · 2020Article
- Molecular Characterization and Expression Profile ofPlants (Basel, Switzerland) · 2020Article
- Divergent Functional Diversification Patterns in the SEP/AGL6/AP1 MADS-Box Transcription Factor Superclade.The Plant cell · 2019Article
- Overexpression ofProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Developmental and Molecular Changes Underlying the Vernalization-Induced Transition to Flowering inGenes · 2019Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Floral homeotic genes that control the specification of meristem and organ identity in developing flowers have been isolated from both Arabidopsis thaliana and Antirrhinum majus. Most of these genes belong to a large family of regulatory genes and possess a characteristic DNA binding domain known as the MADS-box. Members of this gene family display primarily floral-specific expression and are homologous to transcription factors found in several animal and fungal species. Molecular evolutionary analyses reveal that there are appreciable differences in the substitution rates between different domains of these plant MADS-box genes. Phylogenetic analyses also demonstrate that members of the plant MADS-box gene family are organized into several distinct gene groups: the AGAMOUS, APETALA3/PISTILLATA and APETALA1/AGL9 groups. The shared evolutionary history of members of a gene group appear to reflect the distinct functional roles these MADS-box genes play in flower development. Molecular evolutionary analyses also suggest that these different gene groups were established in a relatively short span of evolutionary time and that the various floral homeotic loci originated even before the appearance of the flowering plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.