ArticleAnnals of biomedical engineering
Lysolipid exchange with lipid vesicle membranes.
Article in Annals of biomedical engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 95 citations in OpenAlex.
- Mitochondrial alterations induced by Macrovipera lebetina venom.European biophysics journal : EBJ · 2025Article
- Phospholipase-catalyzed degradation drives domain morphology and rheology transitions in model lung surfactant monolayers.Soft matter · 2024Article
- Manipulation of encapsulated artificial phospholipid membranes using sub-micellar lysolipid concentrations.Communications chemistry · 2024Article
- Surfactant-Mediated Structural Modulations to Planar, Amphiphilic Multilamellar Stacks.The journal of physical chemistry. B · 2023Article
- A hemifused complex is the hub in a network of pathways to membrane fusion.Biophysical journal · 2023Article
- Surfactant-Mediated Solubilization of Myelin Figures: A Multistep Morphological Cascade.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Article
- Cyanine Dyes for Photo-Thermal Therapy: A Comparison of Synthetic Liposomes and Natural Erythrocyte-Based Carriers.International journal of molecular sciences · 2021Article
- PIP2 Reshapes Membranes through Asymmetric Desorption.Biophysical journal · 2019Article
- Review
- Measuring bilayer surface energy and curvature in asymmetric droplet interface bilayers.Journal of the Royal Society, Interface · 2018Article
- Inside-outside self-assembly of light-activated fast-release liposomes.Physical chemistry chemical physics : PCCP · 2015Article
- Lipids, curvature, and nano-medicine.European journal of lipid science and technology : EJLST · 2011Article
- Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending elasticity.Biophysical journal · 2007Article
- Elasticity and phase behavior of DPPC membrane modulated by cholesterol, ergosterol, and ethanol.Biophysical journal · 2005Article
- Effect of salicylate on the elasticity, bending stiffness, and strength of SOPC membranes.Biophysical journal · 2005Article
- The influence of short-chain alcohols on interfacial tension, mechanical properties, area/molecule, and permeability of fluid lipid bilayers.Biophysical journal · 2004Article
- Material studies of lipid vesicles in the L(alpha) and L(alpha)-gel coexistence regimes.Biophysical journal · 2003Article
- Controlling and measuring local composition and properties in lipid bilayer membranes.Journal of biological physics · 2002Article
- Asymmetrical membranes and surface tension.Biophysical journal · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
While the aqueous solubility for bilayer phospholipids is less than 10(-10) M--keeping lipid membranes at essentially constant mass, single chain surfactants can have a significant aqueous solubility. Thus, in surfactant solutions, both monomer and micelles can interact with a lipid bilayer, and the mass and composition of the bilayer can be changed in seconds. These changes in composition are expected to have direct consequences on bilayer structure and material properties. We have found that the exchange of surfactants like lysolecithin can be described in terms of a kinetic model in which monomer and micelles are transported to the membrane from bulk solution. Molecular transport is considered at the membrane interfaces and across the midplane between the two monolayers of the bilayer. Using micropipet manipulation, single vesicles were transferred into lysolecithin solutions, and the measurement of vesicle area change gave a direct measure of lysolecithin uptake. Transfer back to lysolecithin-free media resulted in desorption. The rates of uptake and desorption could therefore be measured at controlled levels of membrane stress. With increasing lysolecithin concentration in the bulk phase, the amount of lysolecithin in the membrane reached saturation at approximately 3 mol% for concentrations below the critical micelle concentration (CMC) and at > 30 mol% for concentrations above the CMC. When convective transport was used to deliver lysolecithin, uptake occurred via a double exponential: initial uptake into the outer monolayer was fast (approximately 0.2 sec-1); transfer across the bilayer midplane was much slower (0.0019 sec-1).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.