ArticleThe Journal of cell biology1995
Members of the NAP/SET family of proteins interact specifically with B-type cyclins.
Article in The Journal of cell biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 164 citations in OpenAlex.
- Nap1 and Kap114 co-chaperone H2A-H2B and facilitate targeted histone release in the nucleus.The Journal of cell biology · 2025Article
- MoNap1, a Nucleosome Assemble Protein 1, Regulates Growth, Development, and Pathogenicity inJournal of fungi (Basel, Switzerland) · 2022Article
- Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity.Cell death & disease · 2019Article
- The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation.Scientific reports · 2018Article
- Characterization of additional components of the environmental pH-sensing complex in the pathogenic fungusThe Journal of biological chemistry · 2018Article
- TSPY1 suppresses USP7-mediated p53 function and promotes spermatogonial proliferation.Cell death & disease · 2018Article
- Glutamylation of Nap1 modulates histone H1 dynamics and chromosome condensation in Xenopus.The Journal of cell biology · 2015Article
- Patronin mediates a switch from kinesin-13-dependent poleward flux to anaphase B spindle elongation.The Journal of cell biology · 2013Article
- Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A.PLoS genetics · 2013Article
- Cell polarization and cytokinesis in budding yeast.Genetics · 2012Review
- A full suite of histone and histone modifying genes are transcribed in the dinoflagellate Lingulodinium.PloS one · 2012Article
- Article
- An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain.Molecular cell · 2010Article
- TSPY and its X-encoded homologue interact with cyclin B but exert contrasting functions on cyclin-dependent kinase 1 activities.Oncogene · 2008Article
- Optimization of yeast cell cycle analysis and morphological characterization by multispectral imaging flow cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2008Article
- Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis.Carcinogenesis · 2008Article
- Starch biosynthetic enzymes from developing maize endosperm associate in multisubunit complexes.Plant physiology · 2008Article
- Nap1 links transcription elongation, chromatin assembly, and messenger RNP complex biogenesis.Molecular and cellular biology · 2008Article
- The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription.Retrovirology · 2008Article
- Nap1l2 promotes histone acetylation activity during neuronal differentiation.Molecular and cellular biology · 2007Article
5 more citing papers are in PubMed but not listed here.
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclin-dependent kinase complexes that contain the same catalytic subunit are able to induce different events at different times during the cell cycle, but the mechanisms by which they do so remain largely unknown. To address this problem, we have used affinity chromatography to identify proteins that bind specifically to mitotic cyclins, with the goal of finding proteins that interact with mitotic cyclins to carry out the events of mitosis. This approach has led to the identification of a 60-kD protein called NAP1 that interacts specifically with members of the cyclin B family. This interaction has been highly conserved during evolution: NAP1 in the Xenopus embryo interacts with cyclins B1 and B2, but not with cyclin A, and the S. cerevisiae homolog of NAP1 interacts with Clb2 but not with Clb3. Genetic experiments in budding yeast indicate that NAP1 plays an important role in the function of Clb2, while biochemical experiments demonstrate that purified NAP1 can be phosphorylated by cyclin B/p34cdc2 kinase complexes, but not by cyclin A/p34cdc2 kinase complexes. These results suggest that NAP1 is a protein involved in the specific functions of cyclin B/p34cdc2 kinase complexes. In addition to NAP1, we found a 43-kD protein in Xenopus that is homologous to NAP1 and also interacts specifically with B-type cyclins. This protein is the Xenopus homolog of the human SET protein, which was previously identified as part of a putative oncogenic fusion protein (Von Lindern et al., 1992).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.