ArticleBiophysical journal1995
A look at membrane patches with a scanning force microscope.
Article in Biophysical journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 66 citations in OpenAlex.
- Powerful partnership: crosstalk between pannexin 1 and the cytoskeleton.Frontiers in physiology · 2014Review
- Whole-Cell Electrical Activity Under Direct Mechanical Stimulus by AFM Cantilever Using Planar Patch Clamp Chip Approach.Cellular and molecular bioengineering · 2011Article
- Versatile horizontal force probe for mechanical tests on pipette-held cells, particles, and membrane capsules.Biophysical journal · 2009Article
- Twenty odd years of stretch-sensitive channels.Pflugers Archiv : European journal of physiology · 2006Review
- Ca2+-permeable channels in the plasma membrane of Arabidopsis pollen are regulated by actin microfilaments.Plant physiology · 2004Article
- Voltage-induced membrane displacement in patch pipettes activates mechanosensitive channels.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Structure of the erythrocyte membrane skeleton as observed by atomic force microscopy.Biophysical journal · 1998Article
- Voltage-dependent membrane displacements measured by atomic force microscopy.The Journal of general physiology · 1998Article
- A large-conductance K+ channel that is inhibited by the cytoskeleton in the smooth muscle cell line DDT1 MF-2.The Journal of physiology · 1996Article
- Actin microfilament disrupters enhance K(ATP) channel opening in patches from guinea-pig cardiomyocytes.The Journal of physiology · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We combined scanning force microscopy with patch-clamp techniques in the same experimental setup and obtained images of excised membrane patches spanning the tip of a glass pipette. These images indicate that cytoskeleton structures are still present in such membrane patches and form a strong connection between the membrane and the glass wall. This gives the membrane patch the appearance of a tent, stabilized by a scaffold of ropes. The lateral resolution of the images depends strongly on the observed structures and can reach values as low as 10 nm on the cytoskeleton elements of a (inside-out) patch. The observations suggest that measurements of membrane elasticity can be made, opening the way for further studies on mechanical properties of cell membranes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.