ArticleAmerican journal of human genetics1995
Localization of an ataxia-telangiectasia gene to an approximately 500-kb interval on chromosome 11q23.1: linkage analysis of 176 families by an international consortium.
Article in American journal of human genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 79 citations in OpenAlex.
- Ataxia telangiectasia: a rare case report from Nepal.Annals of medicine and surgery (2012) · 2024Article
- A Rare Clinical Finding in Ataxia Telangiectasia: Granulomatous Skin Lesion.Turkish archives of pediatrics · 2024Article
- Bone Marrow Transplantation as Therapy for Ataxia-Telangiectasia: A Systematic Review.Cancers · 2020Review
- From yeast to humans: Understanding the biology of DNA Damage Response (DDR) kinases.Genetics and molecular biology · 2019Article
- Review
- Comprehensive profiling of radiosensitive human cell lines with DNA damage response assays identifies the neutral comet assay as a potential surrogate for clonogenic survival.Radiation research · 2012Article
- Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia.Human mutation · 2012Article
- Cutaneous granulomatosis and combined immunodeficiency revealing Ataxia-Telangiectasia: a case report.Italian journal of pediatrics · 2010Article
- Phenotypic variations between affected siblings with ataxia-telangiectasia: ataxia-telangiectasia in Japan.International journal of hematology · 2009Article
- Clinical radiation sensitivity with DNA repair disorders: an overview.International journal of radiation oncology, biology, physics · 2009Review
- Proton spectroscopy and imaging at 3T in ataxia-telangiectasia.AJNR. American journal of neuroradiology · 2007Article
- ATM haplotypes and associated mutations in Iranian patients with ataxia-telangiectasia: recurring homozygosity without a founder haplotype.Human genetics · 2005Article
- Global analysis of ATM polymorphism reveals significant functional constraint.American journal of human genetics · 2001Article
- Genotype-phenotype relationships in ataxia-telangiectasia and variants.American journal of human genetics · 1998Article
- Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations.American journal of human genetics · 1998Article
- CAND3: A ubiquitously expressed gene immediately adjacent and in opposite transcriptional orientation to the ATM gene at 1lq23.1.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- A high frequency of distinct ATM gene mutations in ataxia-telangiectasia.American journal of human genetics · 1996Article
- Ataxia-telangiectasia and the ATM gene: linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints.Journal of clinical immunology · 1996Review
- Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse chromosome 9.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- Ataxia-telangiectasia: mutations in ATM cDNA detected by protein-truncation screening.American journal of human genetics · 1996Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
We describe a 20-point linkage analysis map of chromosome 11q22-23 that is based on genotyping 249 families (59 CEPH and 190 A-T). Monte Carlo linkage analyses of 176 ataxia-telangiectasia (A-T) families localizes the major A-T locus to the region between S1819(A4) and S1818(A2). When seven nonlinking families were excluded from subsequent analyses, a 2-lod support interval of approximately 500 kb was identified between S1819(A4) and S1294. No recombinants were observed between A-T and markers S384, B7, S535, or S1294. Only 17 of the international consortium families have been assigned to complementation groups. The available evidence favors either a cluster of A-T genes on chromosome 11 or intragenic defects in a single gene.
Indexed as
Identifiers
7611279PMC1801232W1988498014What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.