ArticleNucleic acids research1995
Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins.
Article in Nucleic acids research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 71 citations in OpenAlex.
- Four decades of Eukaryotic DNA replication: From yeast genetics to high-resolution cryo-EM structures of the replisome.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Mechanisms and regulation of DNA replication initiation in eukaryotes.Critical reviews in biochemistry and molecular biology · 2017Review
- Geminin inhibits a late step in the formation of human pre-replicative complexes.The Journal of biological chemistry · 2014Article
- Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication.Cell cycle (Georgetown, Tex.) · 2009Article
- Human INT6 interacts with MCM7 and regulates its stability during S phase of the cell cycle.Oncogene · 2007Article
- Eukaryotic MCM proteins: beyond replication initiation.Microbiology and molecular biology reviews : MMBR · 2004Review
- Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B.The Journal of cell biology · 2001Article
- The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.Nucleic acids research · 2000Article
- Article
- Differential effects of virulent versus avirulent Legionella pneumophila on chemokine gene expression in murine alveolar macrophages determined by cDNA expression array technique.Infection and immunity · 2000Article
- Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity.Molecular and cellular biology · 1999Article
- Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation.The EMBO journal · 1998Article
- Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.Molecular and cellular biology · 1998Article
- Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants.Genes & development · 1997Article
- Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: identification of Cdc45p as a subunit.Molecular and cellular biology · 1997Article
- Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7.The EMBO journal · 1997Article
- Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two new mouse genes encoding proteins that belong to the yeast minichromosome maintenance (MCM) protein family, which is involved in the initiation of DNA replication, were isolated and their nucleotide sequence was determined. They were a putative CDC46/MCM5 homolog and a putative cdc21 homolog. About 30% amino acid identity was obtained between members in the family, and > 40% between the putative mouse and yeast homologs. The expression of these genes was cell-cycle specific at the late G1 to S phase. Immunochemical analyses showed the physical interaction between mouse P1MCM3 and CDC46 protein. These results suggest that MCM proteins function in co-ordination for DNA replication.
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