ArticleJournal of virology1995
Enhanced intracellular calcium concentration during poliovirus infection.
Article in Journal of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Seneca Valley virus induces mitochondrial apoptosis by activating ER stress or the PERK pathway based on CaJournal of virology · 2025Article
- Calcium Chloride Treatment Enhances Antigen Production in Foot-and-Mouth Disease Vaccines for Serotypes SAT1 and SAT3.Vaccines · 2024Article
- Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium.Biochimica et biophysica acta. Biomembranes · 2022Article
- From Molecular Pathology of COVID 19 to Nigella Sativum as a Treatment Option: Scientific Based Evidence of Its Myth or Reality.Chinese journal of integrative medicine · 2022Review
- The Heat Shock Protein 70 Family of Chaperones Regulates All Phases of the Enterovirus A71 Life Cycle.Frontiers in microbiology · 2020Article
- Apoptosis and Autophagy in Picornavirus Infection.Frontiers in microbiology · 2019Review
- Virus Control of Cell Metabolism for Replication and Evasion of Host Immune Responses.Frontiers in cellular and infection microbiology · 2019Review
- Chandipura Virus Induced Neuronal Apoptosis via Calcium Signaling Mediated Oxidative Stress.Frontiers in microbiology · 2018Article
- Review
- Pathophysiological Consequences of Calcium-Conducting Viroporins.Annual review of virology · 2015Review
- The effects of Nigella sativa (Ns), Anthemis hyalina (Ah) and Citrus sinensis (Cs) extracts on the replication of coronavirus and the expression of TRP genes family.Molecular biology reports · 2014Article
- Viruses as modulators of mitochondrial functions.Advances in virology · 2013Review
- Calcium flux between the endoplasmic reticulum and mitochondrion contributes to poliovirus-induced apoptosis.Journal of virology · 2010Article
- Release of intracellular calcium stores facilitates coxsackievirus entry into polarized endothelial cells.PLoS pathogens · 2010Article
- Viral calciomics: interplays between Ca2+ and virus.Cell calcium · 2009Review
- Identification and functional analysis of salmon annexin 1 induced by a virus infection in a fish cell line.Journal of virology · 2007Article
- The alphavirus 6K protein activates endogenous ionic conductances when expressed in Xenopus oocytes.The Journal of membrane biology · 2007Article
- Involvement of intracellular free Ca2+ in enhanced release of herpes simplex virus by hydrogen peroxide.Virology journal · 2006Article
- Amino acid changes in proteins 2B and 3A mediate rhinovirus type 39 growth in mouse cells.Journal of virology · 2005Article
- Identification of genes involved in the host response to enterovirus 71 infection.Journal of neurovirology · 2004Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The infection of human fibroblasts by poliovirus leads to a notable increase in the intracellular calcium concentration, [Ca2+]i, measured by microfluorimetry or by flow cytometry. [Ca2+]i increases from 2 to 3 h postinfection, and by the fifth hour there is a 5- to 10-fold increase in [Ca2+]i. At this time postinfection there is active viral protein synthesis. The modifications in [Ca2+]i are not observed in the presence of cycloheximide, guanidine, or Ro 09-0179, indicating that virus gene expression is required for the increase in [Ca2+]i. Attempts to identify the source of the intracellular Ca2+ by using different inhibitors of calcium fluxes suggest that calcium enters from the culture medium through voltage-sensitive calcium channels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.