Evidence map›Paper›PMID 7596345›Full record

ArticleMolecular and cellular biochemistry1995

Pancreatic tau related maps: biochemical and immunofluorescence analysis in a tumoral cell line.

L Michalik, P Neuville, M T Vanier, J F Launay

Abstract read
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In one paragraph

Article in Molecular and cellular biochemistry, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

L MichalikINSERM U.381, Ontogénèse et pathologie du systéme digestif, Strasbourg, France.
P Neuville
M T Vanier
J F Launay
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we report the existence of four tau-related microtubule-associated proteins (MAPs) of 48, 50, 55 and 58 kDa in a pancreatic exocrine cell line (AR4-2J). Using immunofluorescence, we demonstrate that these tau-related MAPs are associated with microtubules in AR4-2J cells. That colocalization is particularly striking on microtubules bundles in cellular extensions and is the first evidence for tau-related MAPs colocalization with microtubules in non-neuronal cells. As it has been often discussed for neuronal tau, the localization of tau-related proteins in AR4-2J cells suggests that these proteins may be involved in microtubule bundling.

Indexed as

AnimalsAntibodiesCell LineChromatography, AffinityFluorescent Antibody TechniqueMiceMicrotubule-Associated ProteinsMicrotubulesPaclitaxelPancreatic NeoplasmsRabbitsRatstau ProteinsTubulinVinblastineAntibodiesMicrotubule-Associated ProteinsPaclitaxeltau ProteinsTubulinVinblastine

Identifiers

PMID7596345
OpenAlexW2039635260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.