Evidence map›Paper›PMID 7592499›Full record

ArticleJournal of bacteriology1995

The genes encoding the biotin carboxyl carrier protein and biotin carboxylase subunits of Bacillus subtilis acetyl coenzyme A carboxylase, the first enzyme of fatty acid synthesis.

P Marini, S J Li, D Gardiol, J E Cronan, D de Mendoza

Abstract read
In one paragraph

Article in Journal of bacteriology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Surfactin-Like Lipopeptides FromFrontiers in bioengineering and biotechnology · 2021
    Pooled it
  2. Fatty acid synthesis and utilization in gram-positive bacteria: insights fromMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  3. Article
  4. The Catabolic System of Acetovanillone and Acetosyringone inApplied and environmental microbiology · 2022
    Article
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  14. A channel connecting the mother cell and forespore during bacterial endospore formation.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P MariniDepartamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina.
S J Li
D Gardiol
J E Cronan
D de Mendoza

Funding

NIAID NIH HHS AI 155650
6 · The paper itself

Abstract

The genes encoding two subunits of acetyl coenzyme A carboxylase, biotin carboxyl carrier protein, and biotin carboxylase have been cloned from Bacillus subtilis. DNA sequencing and RNA blot hybridization studies indicated that the B. subtilis accB homolog which encodes biotin carboxyl carrier protein, is part of an operon that includes accC, the gene encoding the biotin carboxylase subunit of acetyl coenzyme A carboxylase.

Indexed as

Carbon-Nitrogen LigasesGenes, BacterialAcetyl-CoA CarboxylaseAmino Acid SequenceBacillus subtilisBacterial ProteinsBase SequenceBiotinCarrier ProteinsCloning, MolecularEscherichia coliFatty AcidsFatty Acid Synthase, Type IIGenetic Complementation TestLigasesMolecular Sequence DataAcetyl-CoA CarboxylaseBacterial ProteinsBiotinbiotin carboxylasebiotin carboxyl carrier proteinCarbon-Nitrogen LigasesCarrier ProteinsFatty AcidsFatty Acid Synthase, Type IILigases

Identifiers

PMID7592499
PMCPMC177574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.