ArticleJournal of bacteriology1995
Evidence that the immunity protein inactivates colicin 5 immediately prior to the formation of the transmembrane channel.
Article in Journal of bacteriology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- High-Yield Preparation of Outer Membrane Protein Efflux Pumps by in Vitro Refolding is Concentration Dependent.The Journal of membrane biology · 2021Article
- Antibacterial activities of bacteriocins: application in foods and pharmaceuticals.Frontiers in microbiology · 2014Review
- Channel domain of colicin A modifies the dimeric organization of its immunity protein.The Journal of biological chemistry · 2010Article
- Colicin biology.Microbiology and molecular biology reviews : MMBR · 2007Review
- Colicin A immunity protein interacts with the hydrophobic helical hairpin of the colicin A channel domain in the Escherichia coli inner membrane.Journal of bacteriology · 2001Article
- Genetic organization of plasmid ColJs, encoding colicin Js activity, immunity, and release genes.Journal of bacteriology · 2001Article
- The iron- and temperature-regulated cjrBC genes of Shigella and enteroinvasive Escherichia coli strains code for colicin Js uptake.Journal of bacteriology · 2001Article
- Identification of specific residues in colicin E1 involved in immunity protein recognition.Journal of bacteriology · 2001Article
- The tip of the hydrophobic hairpin of colicin U is dispensable for colicin U activity but is important for interaction with the immunity protein.Journal of bacteriology · 1998Article
- Colicins--exocellular lethal proteins of Escherichia coli.Folia microbiologica · 1998Review
- Colicin U, a novel colicin produced by Shigella boydii.Journal of bacteriology · 1997Article
- Pesticin displays muramidase activity.Journal of bacteriology · 1997Article
- Target cell specificity of a bacteriocin molecule: a C-terminal signal directs lysostaphin to the cell wall of Staphylococcus aureus.The EMBO journal · 1996Article
- Colicin M is inactivated during import by its immunity protein.Molecular & general genetics : MGG · 1996Article
- Periplasmic location of the pesticin immunity protein suggests inactivation of pesticin in the periplasm.Journal of bacteriology · 1996Article
- Strong function-related homology between the pore-forming colicins K and 5.Journal of bacteriology · 1995Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Determination and analysis of the nucleotide sequences of the activity, immunity, and lysis genes of colicin 5 assigned colicin 5 to the subclass of pore-forming colicins to which colicins 10, E1, Ia, Ib, and K belong. Mutational analysis of colicin 5 and exchange of DNA fragments between the most closely related colicins, colicins 5 and 10, and between their immunity proteins localized the regions that determine the reaction specificity between colicin 5 and its immunity protein to residues 405 to 424 of colicin 5, the region corresponding to the amphiphilic alpha-helix 6 of the similar colicins E1 and Ia. The specificity-conferring residues 55 to 58 and 68 to 75 of the immunity protein were localized in the cytoplasmic loop and the inner leaflet of the cytoplasmic membrane. The localization of the reactive regions of the immunity protein and the colicin close to the inner side of the cytoplasmic membrane suggests that the immunity protein inactivates colicin 5 shortly before the lethal colicin pores in the cytoplasmic membrane are opened.
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