ArticleJournal of anatomy1995
Cryoscanning electron microscopic study of the surface amorphous layer of articular cartilage.
Article in Journal of anatomy, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed.
- Intra-Articular Mesenchymal Stem Cell Injection for Knee Osteoarthritis: Mechanisms and Clinical Evidence.International journal of molecular sciences · 2022Review
- The synovial surface of the articular cartilage.European journal of histochemistry : EJH · 2020Article
- Cartilage Strain Distributions Are Different Under the Same Load in the Central and Peripheral Tibial Plateau Regions.Journal of biomechanical engineering · 2015Article
- Relationship between wettability and lubrication characteristics of the surfaces of contacting phospholipid-based membranes.Cell biochemistry and biophysics · 2013Article
- Influence of dynamic load on friction behavior of human articular cartilage, stainless steel and polyvinyl alcohol hydrogel as artificial cartilage.Journal of materials science. Materials in medicine · 2010Article
- Role of uppermost superficial surface layer of articular cartilage in the lubrication mechanism of joints.Journal of anatomy · 2001Article
- Collagen fibre arrangement in the tibial plateau articular cartilage of man and other mammalian species.Journal of anatomy · 1998Article
- Cryoscanning electron microscopy of loaded articular cartilage with special reference to the surface amorphous layer.Journal of anatomy · 1996Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to elucidate the structure near the articular surface, frozen unfixed hydrated articular cartilage with subchondral bone from the pig knee was examined using a cryoscanning electron microscope (cryo-SEM). This method is considered to reduce the introduction of artefacts due to fixation and drying. An amorphous layer, without a collagen-fibril network or chondrocytes, covered most of the surface of the cartilage. This layer was termed the surface amorphous layer. It showed various appearances, which were classified into 4 groups. The average thickness of the layer did not differ among the 8 anatomical regions from which the specimens were taken. The thickness of the layer was found to correlate with the type of appearance of the layer. The 4 appearances associated with thicknesses in descending order are: 'streaked', 'foliate', 'spotted', and 'vestigial'. The surface layer observed in the cryo-SEM was thicker than that observed by a conventional SEM. This difference may be attributable to dehydration of the specimen used in specimen preparation for the latter technique. The layer was also observed in articular cartilage taken from human and rabbit knees. The layer was found to be unstable and to have very variable features. Its thickness and appearance may be influenced by various factors such as dehydration, fluid absorption or mechanical stress.
Indexed as
Identifiers
7592006PMC1167438What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.