Evidence map›Paper›PMID 7591164›Full record

ArticleInfection and immunity1995

Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli.

J A Girón, F Qadri, T Azim, K J Jarvis, J B Kaper, M J Albert

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Diarrheagenic Escherichia coli.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2016
    Review
  2. Article
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  10. Diarrheagenic Escherichia coli.Clinical microbiology reviews · 1998
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J A GirónCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore 21201, USA.
F Qadri
T Azim
K J Jarvis
J B Kaper
M J Albert
University of Maryland, Baltimore · US

Funding

Molecular Genetics of Enteropathogenic E. Coli AdhesionR37AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 2004 to 2013
$4.8M
MOLECULAR GENETICS OF ENTEROPATHOGENIC E COLI ADHESIONR01AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 1989 to 2003
$1.4M
MOLECULAR GENETICS OF ENTEROPATHOGENIC E. COLI ADHESIONR22AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 1986 to 1991
–
NIAID NIH HHS AI21657NIAID NIH HHS R37 AI021657
6 · The paper itself

Abstract

The bundle-forming pilus (BFP) produced by enteropathogenic Escherichia coli (EPEC) is associated with the presence of a large EPEC adherence factor plasmid and the formation of localized adherence clusters on tissue culture cells. Three mouse monoclonal antibodies (ICA2, ICA3, and ICA4) were produced against BFP purified from EPEC B171 (O111:NM). These monoclonal antibodies reacted in immunoblots with different epitopes of the 19.5-kDa bundlin subunit of BFP of heterologous EPEC. These reagents could serve as diagnostic tools for the identification of EPEC as well as for studying the role of BfpA in the interaction of EPEC with eukaryotic cells.

Indexed as

AnimalsAntibodies, BacterialAntibodies, MonoclonalEscherichia coliFemaleFimbriae, BacterialImmunoblottingMiceMice, Inbred BALB CAntibodies, BacterialAntibodies, Monoclonal

Identifiers

PMID7591164
PMCPMC173713
OpenAlexW1924261721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.