ArticleInfection and immunity1995
An immunodominant 90-kilodalton Aspergillus fumigatus antigen is the subunit of a catalase.
Article in Infection and immunity, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 49 citations in OpenAlex.
- Human-Fungal Pathogen Interactions from the Perspective of Immunoproteomics Analyses.International journal of molecular sciences · 2024Review
- Acute Penicillium marneffei infection stimulates host M1/M2a macrophages polarization in BALB/C mice.BMC microbiology · 2017Article
- Highly Active and Stable Large Catalase Isolated from a Hydrocarbon Degrading Aspergillus terreus MTCC 6324.Enzyme research · 2016Article
- Purification and characterization of a mycelial catalase from Scedosporium boydii, a useful tool for specific antibody detection in patients with cystic fibrosis.Clinical and vaccine immunology : CVI · 2015Article
- Aspergillus fumigatus: principles of pathogenesis and host defense.Eukaryotic cell · 2007Review
- Catalases of Aspergillus fumigatus.Infection and immunity · 2003Article
- Identification and expression of an allergen Asp f 13 from Aspergillus fumigatus and epitope mapping using human IgE antibodies and rabbit polyclonal antibodies.The Biochemical journal · 2000Article
- Production and characterization of recombinant Aspergillus fumigatus Cu,Zn superoxide dismutase and its recognition by immune human sera.Journal of clinical microbiology · 2000Article
- A polymerase chain reaction enzyme immunoassay for diagnosing infection caused by Aspergillus fumigatus.Journal of clinical pathology · 1999Article
- Aspergillus fumigatus and aspergillosis.Clinical microbiology reviews · 1999Review
- Identification and purification of specific Penicillium marneffei antigens and their recognition by human immune sera.Journal of clinical microbiology · 1998Article
- Cloning and disruption of the antigenic catalase gene of Aspergillus fumigatus.Infection and immunity · 1997Article
- Two divergent catalase genes are differentially regulated during Aspergillus nidulans development and oxidative stress.Journal of bacteriology · 1997Article
- Characterization of the Aspergillus nidulans aspnd1 gene demonstrates that the ASPND1 antigen, which it encodes, and several Aspergillus fumigatus immunodominant antigens belong to the same family.Infection and immunity · 1997Article
- Immunoblotting patterns in the serodiagnosis of aspergilloma: antibody response to the 90kDa Aspergillus fumigatus antigen.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1996Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have identified, purified, and characterized structurally and functionally a 90-kDa immunodominant antigen associated with the water-soluble fraction of Aspergillus fumigatus. This antigen is recognized by 90.3% of serum samples from patients with aspergilloma and should be considered either by itself or better in combination with other purified antigens as a candidate for developing a standardized immunoassay for the detection of aspergilloma. p90 is a glycoprotein containing at least two two N-linked sugar chains of 2 and 5 kDa, respectively, which are not necessary for its reactivity with aspergilloma serum samples. Using specific anti-p90 rabbit serum, we have demonstrated that under native conditions, p90 exists in oligomeric form and has associated catalase activity. This activity is resistant to extreme temperatures (> 60 degrees C), reducing agents (40 mM dithiothreitol), high concentrations of denaturing agents such as 8 M urea and 8% sodium dodecyl sulfate, and treatments with ethanol-chloroform-water (5:3:10 [vol/vol]) mixtures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.