ReviewChromosoma1995
Mechanisms of DNA expansion.
Review in Chromosoma, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Data mining revealed no other trinucleotide repeat expansion associated with the Huntington's disease biomarker (CAG).Clinical parkinsonism & related disorders · 2026Article
- Inherent instability of simple DNA repeats shapes an evolutionarily stable distribution of repeat lengths.Nature communications · 2025Article
- Emerging drivers of DNA repeat expansions.Biochemical Society transactions · 2025Review
- Mechanisms of theInternational journal of molecular sciences · 2022Review
- STRs: Ancient Architectures of the Genome beyond the Sequence.Journal of molecular neuroscience : MN · 2021Review
- Gene Variant ofInternational journal of molecular sciences · 2021Article
- R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities.The Journal of biological chemistry · 2020Article
- E-motif formed by extrahelical cytosine bases in DNA homoduplexes of trinucleotide and hexanucleotide repeats.Nucleic acids research · 2018Article
- Cytomolecular discrimination of the AJournal of applied genetics · 2017Article
- A Glimpse into the Satellite DNA Library in Characidae Fish (Teleostei, Characiformes).Frontiers in genetics · 2017Article
- Next generation sequencing and FISH reveal uneven and nonrandom microsatellite distribution in two grasshopper genomes.Chromosoma · 2015Article
- Trinucleotide expansion in disease: why is there a length threshold?Current opinion in genetics & development · 2014Review
- Impact of bulge loop size on DNA triplet repeat domains: Implications for DNA repair and expansion.Biopolymers · 2014Article
- Association between simple sequence repeat-rich chromosome regions and intergenomic translocation breakpoints in natural populations of allopolyploid wild wheats.Annals of botany · 2011Article
- Bin mapping of genomic and EST-derived SSRs in melon (Cucumis melo L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2008Article
- Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease.DNA repair · 2008Review
- Replication fork stalling at natural impediments.Microbiology and molecular biology reviews : MMBR · 2007Review
- Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.Molecular and cellular biology · 2007Article
- Mechanistic features of CAG*CTG repeat contractions in cultured cells revealed by a novel genetic assay.Nucleic acids research · 2005Article
- Replication stalling at Friedreich's ataxia (GAA)n repeats in vivo.Molecular and cellular biology · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Unstable transmission of repeating segments in genes is now recognized as a new class of mutations causing human disease. Genetic instability observed in disease is termed an "expansion mutation" when the mutation is an increase in the copy number of a repeated unit, commonly a di- or trinucleotide. While the expansion mutation is well characterized in disease, the mechanism by which expansion occurs is not clear. This article focuses on physical properties of expansion at repeating nucleotides that may provide clues to the mechanism. Both biochemical and genetic data indicate that DNA structure is part of the mechanism and the underlying cause for expansion.
Indexed as
Identifiers
7587591What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.