The gene as the drug.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. Immune-enhancing effect of nano-DNA vaccine encoding a gene of the prME protein of Japanese encephalitis virus and BALB/c mouse granulocyte-macrophage colony-stimulating factor.Molecular medicine reports · 2015
   Article
2. Gene therapy, early promises, subsequent problems, and recent breakthroughs.Advanced pharmaceutical bulletin · 2013
   Article
3. Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands.Oral diseases · 2010
   Article
4. Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure.Gene therapy · 2006
   Article
5. Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands.Gene therapy · 2006
   Article
6. Preparation and characterization of chitosan and trimethyl-chitosan-modified poly-(epsilon-caprolactone) nanoparticles as DNA carriers.AAPS PharmSciTech · 2005
   Article
7. In vitro adenovirus mediated gene transfer to the human cornea.The British journal of ophthalmology · 2005
   Article
8. Adenoviral transfer of human interleukin-10 gene in lethal pancreatitis.World journal of gastroenterology · 2004
   Article
9. Preclinical safety testing of biotechnology-derived pharmaceuticals: understanding the issues and addressing the challenges.Molecular biotechnology · 2004
   Review
10. Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article
11. Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope.Biophysical journal · 2003
    Article
12. On the transport of lipoplexes through cystic fibrosis sputum.Pharmaceutical research · 2002
    Article
13. Effects of cationic liposome-DNA complexes on pulmonary surfactant function in vitro and in vivo.Lipids · 1997
    Article
14. From sticky stuff to sweet receptors--achievements, limits and novel approaches to bioadhesion.European journal of drug metabolism and pharmacokinetics
    Review

Corrections and comments

• Comment on
  Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.1995

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as