ArticleArchives of disease in childhood. Fetal and neonatal edition1995
Predictive value of early neuroimaging, pulsed Doppler and neurophysiology in full term infants with hypoxic-ischaemic encephalopathy.
Article in Archives of disease in childhood. Fetal and neonatal edition, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 221 citations in OpenAlex.
- Pooled it
- Amplitude-integrated electroencephalography compared with conventional video-electroencephalography for detection of neonatal seizures.The Cochrane database of systematic reviews · 2025Pooled it
- Amplitude Integrated Electroencephalogram as a Prognostic Tool in Neonates with Hypoxic-Ischemic Encephalopathy: A Systematic Review.PloS one · 2016Pooled it
- The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial.BMC pediatrics · 2008Trial
- Transcranial ultrasound as a diagnostic tool for hypoxic-ischemic encephalopathy in preterm neonates: A cross-sectional study.Bioinformation · 2025Article
- Ultrasound Diagnosis and Near-Infrared Spectroscopy in the Study of Encephalopathy in Neonates Born under Asphyxia: Narrative Review.Children (Basel, Switzerland) · 2024Review
- Use of Cranial Ultrasound Prior to the Start of Therapeutic Hypothermia for Newborn Encephalopathy.Cureus · 2023Review
- Prognostic value of somatosensory-evoked potentials in the newborn with hypoxic-ischemic encephalopathy after the introduction of therapeutic hypothermia.European journal of pediatrics · 2022Article
- Challenges in developing therapeutic strategies for mild neonatal encephalopathy.Neural regeneration research · 2022Review
- Surviving and Thriving: Early Intervention for Neonatal Survivors With Developmental Disability in Uganda.Infants and young children · 2021Article
- A new index of ultrasonography for estimating cerebral circulation in newborn infants.Journal of medical ultrasonics (2001) · 2020Article
- The development and validation of a cerebral ultrasound scoring system for infants with hypoxic-ischaemic encephalopathy.Pediatric research · 2020Article
- Ultrasound Predicts White Matter Integrity after Hypothermia Therapy in Neonatal Hypoxic-Ischemic Injury.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2019Article
- Association of cerebral activity with MRI scans in infants with neonatal encephalopathy undergoing therapeutic hypothermia.European journal of pediatrics · 2019Article
- A Comparison Of Conventional Electroencephalography With Amplitude-Integrated EEG In Detection Of Neonatal Seizures.Medical devices (Auckland, N.Z.) · 2019Review
- Prospective research on infants with mild encephalopathy: the PRIME study.Journal of perinatology : official journal of the California Perinatal Association · 2018Observational
- Evaluation of SEPs in asphyxiated newborns using a 4-electrode aEEG brain monitoring set-up.Clinical neurophysiology practice · 2018Article
- Application of an Amplitude-integrated EEG Monitor (Cerebral Function Monitor) to Neonates.Journal of visualized experiments : JoVE · 2017Article
- Fifty years of brain imaging in neonatal encephalopathy following perinatal asphyxia.Pediatric research · 2017Review
- Hypothermia for neonatal hypoxic-ischemic encephalopathy: NICHD Neonatal Research Network contribution to the field.Seminars in perinatology · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate their prognostic value, five different non-invasive techniques were used on 34 full term infants with hypoxic-ischaemic encephalopathy (HIE) within six hours of delivery. Cranial ultrasonography, the resistance index (RI) of the middle cerebral artery obtained with Doppler ultrasonography, somatosensory evoked potentials (SEPs), visual evoked potentials (VEPs) and the cerebral function monitor (CFM) were used. According to the criteria of Sarnat, 11 infants developed mild, seven moderate, and 16 severe encephalopathy. The CFM had the highest positive (PPV 84.2%) and negative predictive value (NPV 91.7%). All but one of the infants with a continuous pattern had a good outcome. The CFM of 11 cases with a suppression-burst pattern changed to a continuous pattern over 24 to 48 hours in four infants, and was associated with a normal outcome in three. All five cases with an isoelectric CFM died. The SEPs also provided useful information (PPV 81.8%; NPV 91.7%). VEPs were often delayed during the first hours or life and did not carry a poor prognosis in five of 14 cases (PPV 77.3%). Both ultrasonography and Doppler RI were of little value, as they were almost always normal at this early stage. In 34 full term infants with HIE, studied within 6 hours of life, the CFM and SEPs provided the most useful information about the expected course of encephalopathy and subsequent neurodevelopmental outcome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.