ArticleProceedings of the National Academy of Sciences of the United States of America1995
Mutational analysis of phytochrome B identifies a small COOH-terminal-domain region critical for regulatory activity.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 75 citations in OpenAlex.
- Phytochrome B sets condensate number through graded nucleator states and seeding-site efficacy.Nature communications · 2026Article
- Intragenic suppressor screen of YHB identifies novel and known loss-of-function alleles of Arabidopsis phytochrome B.bioRxiv : the preprint server for biology · 2026Article
- Modulation of warm temperature-sensitive growth using a phytochrome B dark reversion variant, phyB[G515E], in Arabidopsis and rice.Journal of advanced research · 2024Article
- A cytosol-tethered YHB variant of phytochrome B retains photomorphogenic signaling activity.Plant molecular biology · 2024Article
- Article
- Characterization of peanut phytochromes and their possible regulating roles in early peanut pod development.PloS one · 2018Article
- Unearthing the transition rates between photoreceptor conformers.BMC systems biology · 2016Article
- OsPhyA modulates rice flowering time mainly through OsGI under short days and Ghd7 under long days in the absence of phytochrome B.Plant molecular biology · 2016Article
- A Constitutively Active Allele of Phytochrome B Maintains Circadian Robustness in the Absence of Light.Plant physiology · 2015Article
- Structure-guided engineering of plant phytochrome B with altered photochemistry and light signaling.Plant physiology · 2013Article
- Arabidopsis phytochrome B promotes SPA1 nuclear accumulation to repress photomorphogenesis under far-red light.The Plant cell · 2013Article
- Interaction with plant transcription factors can mediate nuclear import of phytochrome B.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- A novel high-throughput in vivo molecular screen for shade avoidance mutants identifies a novel phyA mutation.Journal of experimental botany · 2011Article
- Light-regulated nuclear import and degradation of Arabidopsis phytochrome-A N-terminal fragments.Plant & cell physiology · 2011Article
- An integrative model for phytochrome B mediated photomorphogenesis: from protein dynamics to physiology.PloS one · 2010Article
- SHORT HYPOCOTYL UNDER BLUE1 truncations and mutations alter its association with a signaling protein complex in Arabidopsis.The Plant cell · 2010Article
- The histidine kinase-related domain of Arabidopsis phytochrome a controls the spectral sensitivity and the subcellular distribution of the photoreceptor.Plant physiology · 2009Article
- Mutant screen distinguishes between residues necessary for light-signal perception and signal transfer by phytochrome B.PLoS genetics · 2008Article
- The PHYTOCHROME C photoreceptor gene mediates natural variation in flowering and growth responses of Arabidopsis thaliana.Nature genetics · 2006Article
- Heterodimerization of type II phytochromes in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Overexpression of phytochrome B (phyB) in transgenic Arabidopsis results in enhanced deetiolation in red light. To define domains of phyB functionally important for its regulatory activity, we performed chemical mutagenesis of a phyB-overexpressing line and screened for phenotypic revertants in red light. Four phyB-transgene-linked revertants that retain parental levels of full-length, dimeric, and spectrally normal overexpressed phyB were identified among 101 red-light-specific revertants. All carry single amino acid substitutions in the transgene-encoded phyB that reduce activity by 40- to 1000-fold compared to the nonmutagenized parent. The data indicate that the mutant molecules are fully active in photosignal perception but defective in the regulatory activity responsible for signal transfer to downstream components. All four mutations fall within a 62-residue region in the COOH-terminal domain of phyB, with two independent mutations occurring in a single amino acid, Gly-767. Accumulating evidence indicates that the identified region is a critical determinant in the regulatory function of both phyB and phyA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.