Evidence map›Paper›PMID 7558345›Full record

ArticleInfection and immunity1995

Salmonella strain secreting active listeriolysin changes its intracellular localization.

I Gentschev, Z Sokolovic, H J Mollenkopf, J Hess, S H Kaufmann, M Kuhn, G F Krohne, W Goebel

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
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  4. Microinjection and growth of bacteria in the cytosol of mammalian host cells.Proceedings of the National Academy of Sciences of the United States of America · 2001
    Article
  5. Article
  6. Article
  7. Article
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  9. Mycobacterium bovis Bacille Calmette-Guérin strains secreting listeriolysin of Listeria monocytogenes.Proceedings of the National Academy of Sciences of the United States of America · 1998
    Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

I GentschevLehrstuhl für Mikrobiologie, Theodor-Boveri-Institut für Biowissenschaften, Würzburg, Germany.
Z Sokolovic
H J Mollenkopf
J Hess
S H Kaufmann
M Kuhn
G F Krohne
W Goebel
Würzburg Institute for Traffic Sciences (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the construction of an attenuated Salmonella dublin aroA strain which secretes via the Escherichia coli hemolysin secretion machinery an active hybrid cytolysin consisting of listeriolysin from Listeria monocytogenes and the C-terminal secretion signal of E. coli hemolysin. This hemolytic S. dublin strain is partially released into the cytoplasm of the host cell following uptake by J774 macrophage cells, whereas the nonhemolytic control S. dublin aroA strain remains in the phagosome.

Indexed as

Bacterial ToxinsAnimalsBase SequenceCell LineHeat-Shock ProteinsHemolysin ProteinsMacrophagesMiceMolecular Sequence DataSalmonellaBacterial ToxinsHeat-Shock ProteinsHemolysin ProteinshlyA protein, Listeria monocytogenes

Identifiers

PMID7558345
PMCPMC173596
OpenAlexW1933476162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.