ReviewHistochemistry and cell biology1995
The NADPH oxidase complex of phagocytic leukocytes: a biochemical and cytochemical view.
Review in Histochemistry and cell biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 104 citations in OpenAlex.
- Investigation of Cell Damage Induced by Silver Nanoparticles in a Model Cell System.Pharmaceutics · 2025Article
- Protective Role of MAVS Signaling for Murine Lipopolysaccharide-Induced Acute Kidney Injury.ImmunoHorizons · 2024Article
- Variant Type X91Journal of clinical immunology · 2022Article
- Cytosolic Fe-superoxide dismutase safeguardsProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Ethylene, an early marker of systemic inflammation in humans.Scientific reports · 2017Article
- Article
- Article
- Granulocyte colony stimulating factor attenuates hyperoxia-induced lung injury by down-modulating inflammatory responses in neonatal rats.Yonsei medical journal · 2011Article
- Phagocytic leukocytes and reactive oxygen species.Histochemistry and cell biology · 2009Review
- Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70.Anesthesiology · 2008Review
- Reactive oxygen species in phagocytic leukocytes.Histochemistry and cell biology · 2008Review
- Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis.Journal of leukocyte biology · 2005Article
- Mitochondrial transmembrane potential is diminished in phorbol myristate acetate-stimulated peritoneal resident macrophages isolated from wild-type mice, but not in those from gp91-phox-deficient mice.Histochemistry and cell biology · 2004Article
- Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy.Histochemistry and cell biology · 2004Review
- Article
- Detection of oxidant producing-sites in glutaraldehyde-fixed human neutrophils and eosinophils stimulated with phorbol myristate acetate.The Histochemical journal · 1999Article
- A novel form of hereditary myeloperoxidase deficiency linked to endoplasmic reticulum/proteasome degradation.The Journal of clinical investigation · 1998Article
- Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly.The Journal of clinical investigation · 1998Article
- The effect of copper deficiency on the peripheral blood cells of cattle.Veterinary research communications · 1998Article
- Interaction of human neutrophil flavocytochrome b with cytosolic proteins: transferred-NOESY NMR studies of a gp91phox C-terminal peptide bound to p47phox.The Biochemical journal · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The NADPH oxidase complex catalyzes the formation of superoxide (O2.-) in phagocytic leukocytes. This paper reviews recent advances in our understanding of this enzyme system. Recent studies have defined conditions for reconstitution of this enzymatic activity with purified proteins in a cell-free system. The role of the individual proteins that make up the active complex, their regulation and the effects of mutations in these proteins are discussed. While these studies represent major achievements, it is clear from cytochemical investigations that additional levels of complexity exist in the modulation of the NADPH oxidase complex in vivo. A major role for cytochemical analysis in understanding the cell biological aspects of the generation of reactive oxygen species is discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.