Evidence map›Paper›PMID 7549637›Full record

ArticleBMJ (Clinical research ed.)1995

Review of prescribed treatment for children with asthma in 1990.

J O Warner

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Management of severe asthma in children.Lancet (London, England) · 2010
    Review
  3. Management of unresponsive asthma.Indian journal of pediatrics · 2004
    Review
  4. Article
  5. Review
  6. The impact of corticosteroids on growth and bone health.Archives of disease in childhood · 2002
    Article
  7. Article
  8. Review
  9. Article
  10. Nebulizers in general practice--impending redundancy?The British journal of general practice : the journal of the Royal College of General Practitioners · 1997
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

J O WarnerDepartment of Child Health, University of Southampton, Southampton General Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo review treatment prescribed to asthmatic children in Great Britain during the 12 months after publication of the first guidelines and to assess effectiveness of prophylactic treatment.

designReview of prescribing information from January 1990 to June 1991 in a representative sample of general practices in Great Britain with a Compufile/AAH Meditel computer. SUBJECTS: 17,846 children with asthma aged 4-17 years.

main outcome measuresNumbers of children prescribed different asthma treatments; estimated use of inhaled beta agonists in those receiving prophylactic treatment.

resultsFrom January to December 1990, 9,362 (52.5%) children were prescribed preventive treatments. 16,211 (90.8%) children were prescribed bronchodilators of some kind. 3,055 (17.1%) were prescribed sodium cromoglycate, and the proportion decreased significantly during the study (from 19.5% (95% confidence interval 18.6% to 20.4%) to 17.2% (16.4% to 18.1%), P < 0.001, in children aged 4-11 years and from 14.9% (14.0% to 15.9%) to 11.3% (10.4% to 12.2%), P < 0.001, in those aged 12-17 during January-July 1991). 6,952 (39.0%) were prescribed inhaled steroids, and the proportion increased during the study (from 35.1% (34.0% to 36.2%) to 44.1% (43.0% to 45.2%), P < 0.001, in children aged 4-11 years and from 38.7% (37.4% to 40.0%) to 44.1% (42.7% to 45.5%), P < 0.001, in those aged 12-17 during January-July 1991). Only 1,358 of the 9,362 children (14.5%) received sufficient repeat prescriptions to suggest that they might be taking the prophylactic treatment regularly. Among these children short acting inhaled beta agonists were being used on average four to eight times a day.

conclusionsThese results are useful baseline data for audit of the impact of published clinical guidelines, particularly in terms of reducing the need for short acting inhaled beta agonists with prophylactic treatment.

Indexed as

Drug Utilization ReviewPractice Guidelines as TopicAdministration, InhalationAdolescentAdrenergic beta-AntagonistsAsthmaBronchodilator AgentsChildChild, PreschoolControlled Clinical Trials as TopicDrug PrescriptionsFamily PracticeHumansPatient ComplianceAdrenergic beta-AntagonistsBronchodilator Agents

Identifiers

PMID7549637
PMCPMC2551432

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.