Evidence map›Paper›PMID 7547031›Full record

ArticleBritish heart journal1995

Factors determining case fatality in myocardial infarction "who dies in a heart attack"?

G Wannamethee, P H Whincup, A G Shaper, M Walker, P W MacFarlane

Open access · bronzeAbstract read
In one paragraph

Article in British heart journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 87 citations in OpenAlex.

  1. Trial
  2. Gender differences in prevalence of myocardial infarction in rural West Texans.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Article
  3. Article
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  6. Case fatality of myocardial infarction among shift workers.International archives of occupational and environmental health · 2015
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  16. Treatment of lipid disorders in patients with diabetes.Current treatment options in cardiovascular medicine · 2006
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  19. Article
  20. Activation of epsilon protein kinase C correlates with a cardioprotective effect of regular ethanol consumption.Proceedings of the National Academy of Sciences of the United States of America · 1998
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

G WannametheeDepartment of Public Health, Royal Free Hospital School of Medicine, London.
P H Whincup
A G Shaper
M Walker
P W MacFarlane
The Royal Free Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the determinants of case fatality in the first major ischaemic heart disease event (heart attack) after screening.

methodsProspective study of 7735 middle aged men drawn from general practices in 24 British towns.

resultsDuring 11.5 years follow up there were 743 major ischaemic heart disease events of which 302 (40.6%) were fatal within 28 days of onset. Previous definite myocardial infarction or stroke and age at time of event were most strongly associated with case fatality. In men with no previous myocardial infarction or stroke, after adjustment for a range of risk factors, antihypertensive treatment (odds ratio (OR) = 1.97, P < 0.05), arrhythmia (OR = 1.93, P = 0.06), increased heart rate (OR = 2.03, P = 0.06), and diabetes (OR = 2.61, P = 0.07) were associated with increased case fatality. High levels of physical activity (OR = 0.53, P < 0.05) and moderate drinking (16-42 units/week) (OR = 0.61, P < 0.05) were associated with lower case fatality, although moderate drinking was not associated with a lower incidence of major ischaemic heart disease events. Current smoking, serum total cholesterol, and systolic blood pressure were not significantly associated with case fatality. In men with previous myocardial infarction or stroke, arrhythmia and to a lesser degree antihypertensive treatment, moderate or heavy drinking, and diabetes were associated with higher case fatality.

conclusionThese findings suggest that physical activity may be an important modifiable factor influencing the incidence of ischaemic heart disease and the chance of survival in men without a previous heart attack or stroke. Arrhythmia, increased heart rate, diabetes, and treatment for hypertension are also areas of concern.

Indexed as

AdultAge FactorsAlcohol DrinkingAntihypertensive AgentsArrhythmias, CardiacCerebrovascular DisordersDiabetes ComplicationsExerciseHumansMaleMiddle AgedMyocardial InfarctionPrecipitating FactorsProspective StudiesRecurrenceRisk FactorsAntihypertensive Agents

Identifiers

PMID7547031
PMCPMC484027
OpenAlexW2106969522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.