ArticleJournal of virology1995
Isolation of novel human endogenous retrovirus-like elements with foamy virus-related pol sequence.
Article in Journal of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 104 citations in OpenAlex.
- Gammaretrovirus Infections in Humans in the Past, Present, and Future: Have We Defeated the Pathogen?Pathogens (Basel, Switzerland) · 2026Review
- Retrotransposon renaissance in early embryos.Trends in genetics : TIG · 2024Review
- Contemporary Distribution, Estimated Age, and Prehistoric Migrations of Old World Monkey Retroviruses.Epidemiologia (Basel, Switzerland) · 2021Review
- Identification of Differentially Expressed Human Endogenous Retrovirus Families in Human Leukemia and Lymphoma Cell Lines and Stem Cells.Frontiers in oncology · 2021Article
- Nomenclature for endogenous retrovirus (ERV) loci.Retrovirology · 2018Review
- Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L.Retrovirology · 2018Article
- Classification and characterization of human endogenous retroviruses; mosaic forms are common.Retrovirology · 2016Article
- Differential expression analysis of human endogenous retroviruses based on ENCODE RNA-seq data.BMC medical genomics · 2015Article
- dUTPase: the frequently overlooked enzyme encoded by many retroviruses.Retrovirology · 2015Review
- A novel recombinant retrovirus in the genomes of modern birds combines features of avian and mammalian retroviruses.Journal of virology · 2014Article
- Review
- Identification of an ancient endogenous retrovirus, predating the divergence of the placental mammals.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Article
- Pushing the endogenous envelope.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- Transposable elements as genetic regulatory substrates in early development.Trends in cell biology · 2013Review
- Studies of endogenous retroviruses reveal a continuing evolutionary saga.Nature reviews. Microbiology · 2012Review
- Discovery of retroviral homologs in bats: implications for the origin of mammalian gammaretroviruses.Journal of virology · 2012Article
- HIV infection and HERV expression: a review.Retrovirology · 2012Review
- The rhizome of life: what about metazoa?Frontiers in cellular and infection microbiology · 2012Review
- Characterization of a Xenopus tropicalis endogenous retrovirus with developmental and stress-dependent expression.Journal of virology · 2011Article
- A novel envelope mediated post entry restriction of murine leukaemia virus in human cells is Ref1/TRIM5α independent.Retrovirology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new class of reverse transcriptase coding sequences was detected in reverse-transcribed RNAs from human placenta by polymerase chain amplification with primers in highly conserved regions of the pol gene of mammalian retroviruses and retrotransposons. Using one of these novel sequences as a probe to screen a human genomic library, we isolated retrovirus-like elements bordered by long terminal repeats and having a potential leucine tRNA primer-binding site. Determination of the complete nucleotide sequence (6,591 bp) of one of these elements, termed HERV-L (for human endogenous retrovirus with leucine tRNA primer), revealed domains of amino acid similarities to retroviral reverse transcriptase and integrase proteins. In addition, a region with homologies to dUTPase proteins was found unexpectedly downstream from the integrase domain. Amino acid sequence and phylogenetic analysis indicate that the HERV-L pol gene is related to that of foamy retroviruses. HERV-L-related sequences are detected in several mammalian species and have expanded in primate and mouse genomes up to 100 to 200 copies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.