ArticleHuman genetics1995
C to T and/or G to A transitions are responsible for loss of a MspI restriction site at the 5'-end of the human apolipoprotein AI gene.
Article in Human genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Association of theBalkan journal of medical genetics : BJMG · 2017Article
- Article
- Apolipoprotein A1 gene polymorphisms as risk factors for hypertension and obesity.Clinical and experimental medicine · 2009Article
- Contribution of polymorphisms in the apolipoprotein AI-CIII-AIV cluster to hyperlipidaemia in patients with gout.Annals of the rheumatic diseases · 2005Article
- Polymorphisms at the 5'-end of the apolipoprotein AI gene and severity of coronary artery disease.The Journal of clinical investigation · 1996Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We detected the loss of a MspI restriction site by a C to T transition at +83 bp and a G to A transition at +84 bp of the 5'-end non-coding region of the human apolipoprotein AI gene. This base change occurred at the "hot spot" (CCGG) for methylation, which may be important in the regulation of gene expression. The population frequency for the loss of the MspI site is 6.1%.
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Registered trials
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